The Use of Poly(N-vinyl pyrrolidone) in the Delivery of Drugs: A Review

P Franco, I De Marco - Polymers, 2020 - mdpi.com
Polyvinylpyrrolidone (PVP) is a hydrophilic polymer widely employed as a carrier in the
pharmaceutical, biomedical, and nutraceutical fields. Up to now, several PVP-based …

Supercritical antisolvent process for pharmaceutical applications: A review

P Franco, I De Marco - Processes, 2020 - mdpi.com
The supercritical antisolvent (SAS) technique has been widely employed in the biomedical
field, including drug delivery, to obtain drug particles or polymer-based systems of …

Nanoparticles and Nanocrystals by Supercritical CO2-Assisted Techniques for Pharmaceutical Applications: A Review

P Franco, I De Marco - Applied Sciences, 2021 - mdpi.com
Many active ingredients currently prescribed show limited therapeutic efficacy, mainly due to
their dissolution rate inadequate to treat the pathology of interest. A large drug particle size …

Supercritical antisolvent coprecipitation mechanisms

V Prosapio, I De Marco, E Reverchon - The Journal of Supercritical Fluids, 2018 - Elsevier
Supercritical antisolvent precipitation (SAS) has been successfully used to produce
microparticles and nanoparticles of controlled size and distribution either as a single …

Preparation of non-steroidal anti-inflammatory drug/β-cyclodextrin inclusion complexes by supercritical antisolvent process

P Franco, I De Marco - Journal of CO2 Utilization, 2021 - Elsevier
In this work, β-cyclodextrin (β-CD) was used as a carrier to produce inclusion complexes
containing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), namely nimesulide (NIM) and …

Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process

V Verma, P Patel, KM Ryan, S Hudson… - The Journal of …, 2023 - Elsevier
Hydrochlorothiazide is a diuretic drug and belongs to Biopharmaceutical Classification
System class IV, having poor water solubility and low permeability, thus proportionally …

Development of nanoparticles for pharmaceutical preparations using supercritical techniques

T Islam, A Al Ragib, S Ferdosh… - Chemical …, 2022 - Taylor & Francis
This review focuses on nanoparticle (NP) synthesis and particle size design using
supercritical fluid (SCF) technology for pharmaceutical formulations. SCF technology is seen …

Co-precipitation of anthocyanins of the extract obtained from blackberry residues by pressurized antisolvent process

APDF Machado, M Rueda, GF Barbero, Á Martín… - The Journal of …, 2018 - Elsevier
An ethanolic anthocyanin-rich extract was obtained from blackberry residues through
ultrasound assisted extraction, and extracts were co-precipitated with the biodegradable …

Complete drying and micronization of ecamsule using supercritical CO2 as the antisolvent

P Hariyanto, AA Myint, J Kim - The Journal of Supercritical Fluids, 2021 - Elsevier
The supercritical antisolvent (SAS) process has been used to produce micronized organic
powders with excellent properties. In this study, the SAS process was used to produce fine …

Supercritical Fluids: A Promising Technique in Pharmaceutics

V Trivedi, AL Ajiboye - Nano-and Microfabrication Techniques in Drug …, 2023 - Springer
The unique properties of supercritical carbon dioxide provide numerous opportunities for
developing environmentally friendly pharmaceutical processes. The applications of …