A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

Exercise is an integral part of the rehabilitation of patients suffering a variety of chronic
musculoskeletal conditions, such as fibromyalgia, chronic low back pain and myofascial …

Physical inactivity or a sedentary lifestyle is a significant health concern worldwide. The
Centers for Disease Control (CDC) recommends 150 minutes per week of moderate to …

Objective Increasing evidence purports exercise as a first-line therapeutic for the treatment
of nearly all forms of chronic pain. However, knowledge of efficacious dosing respective to …

More Americans are consuming diets higher in saturated fats and refined sugars than ever
before, and based on increasing obesity rates, this is a growing trend among older adults as …

The primary objective of preclinical pain research is to improve the treatment of pain.
Decades of research using pain-evoked tests has revealed much about mechanisms but …

Objective This article reviews the structural and functional changes in pain chronification
and explores the association between memory and the development of chronic pain …

Neuropathic pain is caused by a primary lesion or dysfunction of the nervous system and
can occur in the cornea. However, neuropathic corneal pain (NCP) is currently an ill-defined …

Neuropathic pain is a disease of the somatosensory system that is characterized by tingling,
burning, and/or shooting pain. Medication is often the primary treatment, but it can be costly …

BACKGROUND: In neuropathic pain following peripheral nerve injury, microglia are rapidly
activated and accumulated in the spinal cord. Physical exercise can alleviate neuropathic …