[HTML][HTML] Alzheimer's disease pathophysiology in the retina

BP Gaire, Y Koronyo, DT Fuchs, H Shi… - Progress in Retinal and …, 2024 - Elsevier
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Retinal imaging in Alzheimer's and neurodegenerative diseases

PJ Snyder, J Alber, C Alt, LJ Bain… - Alzheimer's & …, 2021 - Wiley Online Library
In the last 20 years, research focused on developing retinal imaging as a source of potential
biomarkers for Alzheimer's disease and other neurodegenerative diseases, has increased …

Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021 - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Retinal biomarkers for Alzheimer's disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis

C Czakó, T Kovács, Z Ungvari, A Csiszar… - Geroscience, 2020 - Springer
Cognitive impairment and dementia are major medical, social, and economic public health
issues worldwide with significant implications for life quality in older adults. The leading …

Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward

J Alber, D Goldfarb, LI Thompson, E Arthur… - Alzheimer's & …, 2020 - Wiley Online Library
The last decade has seen a substantial increase in research focused on the identification,
development, and validation of diagnostic and prognostic retinal biomarkers for Alzheimer's …

Changes in visual function and retinal structure in the progression of Alzheimer's disease

E Salobrar-García, R de Hoz, AI Ramírez… - PloS one, 2019 - journals.plos.org
Background Alzheimer's Disease (AD) can cause degeneration in the retina and optic nerve
either directly, as a result of amyloid beta deposits, or secondarily, as a result of the …

Transport of β-amyloid from brain to eye causes retinal degeneration in Alzheimer's disease

Q Cao, S Yang, X Wang, H Sun, W Chen… - Journal of Experimental …, 2024 - rupress.org
Transport of β-amyloid from brain to eye causes retinal degeneration in Alzheimer’s disease |
Journal of Experimental Medicine | Rockefeller University Press Skip to Main Content …

Advances in retina imaging as potential biomarkers for early diagnosis of Alzheimer's disease

Y Zhang, Y Wang, C Shi, M Shen, F Lu - Translational neurodegeneration, 2021 - Springer
As the most common form of dementia, Alzheimer's disease (AD) is characterized by
progressive cognitive impairments and constitutes a major social burden. Currently, the …

Eye-tracking paradigms for the assessment of mild cognitive impairment: a systematic review

A Wolf, K Tripanpitak, S Umeda… - Frontiers in …, 2023 - frontiersin.org
Mild cognitive impairment (MCI), representing the 'transitional zone'between normal
cognition and dementia, has become a novel topic in clinical research. Although early …

Association of retinal changes with Alzheimer disease neuroimaging biomarkers in cognitively normal individuals

MS Byun, SW Park, JH Lee, D Yi, SY Jeon… - JAMA …, 2021 - jamanetwork.com
Importance Retinal biomarkers reflecting in vivo brain Alzheimer disease (AD) pathologic
abnormalities could be a useful tool for screening cognitively normal (CN) individuals at the …