Regulation of mTORC1 by growth factors, energy status, amino acids and mechanical stimuli at a glance

P Bond - Journal of the International Society of Sports Nutrition, 2016 - Springer
The mechanistic/mammalian target of rapamycin complex 1 (mTORC1) plays a pivotal role
in the regulation of skeletal muscle protein synthesis. Activation of the complex leads to …

Effects of betaine on performance and body composition: a review of recent findings and potential mechanisms

JM Cholewa, L Guimaraes-Ferreira, NE Zanchi - Amino acids, 2014 - Springer
Betaine is a methyl derivative of glycine first isolated from sugar beets. Betaine consumed
from food sources and through dietary supplements presents similar bioavailability and is …

Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial

S Wankhede, D Langade, K Joshi, SR Sinha… - Journal of the …, 2015 - Springer
Background Withania somnifera (a shwagandha) is a prominent herb in Ayurveda. This
study was conducted to examine the possible effects of ashwagandha root extract …

The effects of 14-week betaine supplementation on endocrine markers, body composition and anthropometrics in professional youth soccer players: A double blind …

H Nobari, M Kargarfard, V Minasian… - Journal of the …, 2021 - Taylor & Francis
Objective Betaine supplementation may enhance body composition outcomes when
supplemented chronically during an exercise program. The purpose of this study was to …

Dietary proteins and amino acids in the control of the muscle mass during immobilization and aging: role of the MPS response

JM Cholewa, D Dardevet, F Lima-Soares… - Amino Acids, 2017 - Springer
Dietary proteins/essential amino acids (EAAs) are nutrients with anabolic properties that
may increase muscle mass or attenuate muscle loss during immobilization and aging via the …

Betaine in the brain: characterization of betaine uptake, its influence on other osmolytes and its potential role in neuroprotection from osmotic stress

LS Knight, Q Piibe, I Lambie, C Perkins… - Neurochemical …, 2017 - Springer
Abstract Betaine (N-trimethylglycine), a common osmolyte, has received attention because
of the number of clinical reports associating betaine supplementation with improved …

[HTML][HTML] Higher dietary choline and betaine intakes are associated with better body composition in the adult population of Newfoundland, Canada

X Gao, Y Wang, E Randell, P Pedram, Y Yi, W Gulliver… - PloS one, 2016 - journals.plos.org
Background Choline is an essential nutrient and betaine is an osmolyte and methyl donor.
Both are important to maintain health including adequate lipid metabolism. Supplementation …

The effects of chronic betaine supplementation on body composition and performance in collegiate females: a double-blind, randomized, placebo controlled trial

JM Cholewa, A Hudson, T Cicholski… - Journal of the …, 2018 - Springer
Background Betaine supplementation has been shown to improve body composition and
some metrics of muscular performance in young men; but, whether betaine enhances body …

Effects of 14-weeks betaine supplementation on pro-inflammatory cytokines and hematology status in professional youth soccer players during a competition season …

H Nobari, JM Cholewa, J Pérez-Gómez… - Journal of the …, 2021 - Springer
Objective Systemic elevations in pro-inflammatory cytokines are a marker of non-functional
over reaching, and betaine has been shown to reduce the secretion of pro-inflammatory …

Effects of betaine supplementation on cardiovascular markers: A systematic review and Meta-analysis

D Ashtary-Larky, R Bagheri, M Ghanavati… - Critical Reviews in …, 2022 - Taylor & Francis
Controversy regarding the effects of betaine supplementation on cardiovascular markers
has persisted for decades. This systematic review and meta-analysis compared the effects of …