The cell surface is a mechanobiological unit that encompasses the plasma membrane, its
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …

Astrocytes represent an abundant type of glial cell involved in nearly every aspect of central
nervous system (CNS) function, including synapse formation and maturation, ion and …

Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and
tissue development. The molecular mechanisms determining how and where filopodia grow …

Endosomal sorting complexes for transport-III (ESCRT-III) assemble in vivo onto membranes
with negative Gaussian curvature. How membrane shape influences ESCRT-III …

Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin
filaments. Fresh actin monomers are incorporated at the tips furthest away from the cell …

Filopodia are actin-rich membrane protrusions essential for cell morphogenesis, motility,
and cancer invasion. How cells control filopodium initiation on the plasma membrane …

Morphological transitions are typically attributed to the actions of proteins and lipids. Largely
overlooked in membrane shape regulation is the glycocalyx, a pericellular membrane coat …

The first reported receptor for SARS-CoV-2 on host cells was the angiotensin-converting
enzyme 2 (ACE2). However, the viral spike protein also has an RGD motif, suggesting that …

Microvilli are finger-like membrane protrusions, supported by the actin cytoskeleton, and
found on almost all cell types. A growing body of evidence suggests that the dynamic …

One of the major challenges of bottom-up synthetic biology is rebuilding a minimal cell
division machinery. From a reconstitution perspective, the animal cell division apparatus is …