In recent decades, vaccines have been extraordinary resources to prevent pathogen
diffusion and cancer. Even if they can be formed by a single antigen, the addition of one or …

In recent years, we have found that the dysregulation of the cyclic-GMP-AMP synthase
(cGAS)‒stimulator of interferon genes (STING) pathway leads to the development of …

Arteriviruses can establish persistent infections in animals such as equids, pigs, nonhuman
primates, rodents, and possums. Some Arteriviruses can even cause overt and severe …

Autophagy plays a dual role in coronavirus infection, facilitating the elimination of either
proviral components (virophagy) or antiviral factors such as mitochondria (mitophagy) …

Background Acute kidney injury (AKI) is the main life-threatening complication of crush
syndrome (CS), and myoglobin is accepted as the main pathogenic factor. The pattern …

The development of antiviral strategies is a key task of biomedical research, but broad-
spectrum virus inhibitors are scarce. Here we show that fibroblast growth factor receptor …

Aquaporins (AQPs) are essential membrane proteins facilitating water and small solute
transport across cell membranes. Mammals have approximately 13 paralogs of AQPs that …

Spring viremia of carp virus (SVCV) is a globally distributed virus that causes severe clinical
symptoms and high mortality in fish belonging to the families Cyprinidae and Siluridae. To …

Polyinosinic-polycytidylic acid (poly I: C) is a synthesized analogue of viral double-strand
RNA and considered as a potential immunostimulant in aquaculture. MicroRNAs (miRNAs) …

Background The mature state of dendritic cells (DCs) determines their ability to regulate
immune responses. Retinoic acid-inducible gene-1 (RIG-1) plays a critical role in DC …