Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …

SP Gaudêncio, E Bayram, L Lukić Bilela, M Cueto… - Marine drugs, 2023 - mdpi.com
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

Genome insights into the plant growth-promoting bacterium Saccharibacillus brassicae ATSA2T

L Jiang, J Seo, Y Peng, D Jeon, SJ Park, CY Kim… - AMB Express, 2023 - Springer
Endophytes can facilitate the improvement of plant growth and health in agriculturally
important crops, yet their genomes and secondary metabolites remain largely unexplored …

Characterization of Bioactivities and Biosynthesis of Angucycline/Angucyclinone Derivatives Derived from Gephyromycinifex aptenodytis gen. nov., sp. nov.

WZ Zhu, SH Wang, HM Gao, YM Ge, J Dai, XL Zhang… - Marine Drugs, 2021 - mdpi.com
Strain NJES-13T is the type strain and currently the only species of the newly established
actinobacteria genera Aptenodytes in the family Dermatophilaceae isolated from the gut …

Antibacterial activity and mechanism of a novel bacteriocin produced by Lactiplantibacillus plantarum against Escherichia coli and Staphylococcus aureus

Z Xu, J Wang, W Zheng, S Zhao… - … Journal of Food …, 2023 - Wiley Online Library
The purpose of the study was to explore the antibacterial effect and mechanism of a novel
bacteriocin of Lactiplantibacillus plantarum (L. plantarum) against Escherichia coli (E. coli) …

Phylogenomic analysis uncovers an unexpected capacity for the biosynthesis of secondary metabolites in Pseudoalteromonas

J Wang, P Li, X Di, H Lu, H Wei, S Zhi, DP Fewer… - European Journal of …, 2024 - Elsevier
Pseudoalteromonas is a genus of marine bacteria and a promising source of natural
products with antibacterial, antifungal, and antifouling bioactivities. To accelerate the …

Isolation, phylogenetic and Gephyromycin metabolites characterization of new exopolysaccharides-bearing Antarctic Actinobacterium from feces of emperor penguin

HM Gao, PF Xie, XL Zhang, Q Yang - Marine Drugs, 2021 - mdpi.com
A new versatile actinobacterium designated as strain NJES-13 was isolated from the feces
of the Antarctic emperor penguin. This new isolate was found to produce two active …

Integrated Omics Strategy Reveals Cyclic Lipopeptides Empedopeptins from Massilia sp. YMA4 and Their Biosynthetic Pathway

ST Ho, YN Ho, C Lin, WC Hsu, HJ Lee, CC Peng… - Marine drugs, 2021 - mdpi.com
Empedopeptins—eight amino acid cyclic lipopeptides—are calcium-dependent antibiotics
that act against Gram-positive bacteria such as Staphylococcus aureus by inhibiting cell wall …

New investigation of encoding secondary metabolites gene by genome mining of a marine bacterium, Pseudoalteromonas viridis BBR56

DP Handayani, A Isnansetyo, I Istiqomah - BMC genomics, 2024 - Springer
Pseudoalteromonas viridis strain BBR56 was isolated from seawater at Dutungan Island,
South Sulawesi, Indonesia. Bacterial DNA was isolated using Promega Genomic DNA …

Biosynthetic mechanism of the yellow pigments in the marine bacterium Pseudoalteromonas sp. strain T1lg65

Y Ren, R Liu, Y Zheng, H Wang, Q Meng… - Applied and …, 2024 - Am Soc Microbiol
The Pseudoalteromonas genus marine bacteria have attracted increasing interest because
of their abilities to produce bioactive metabolites. The pigmented Pseudoalteromonas group …

New Report: Genome Mining Untaps the Antibiotics Biosynthetic Gene Cluster of Pseudoalteromonas xiamenensis STKMTI.2 from a Mangrove Soil Sediment

DP Handayani, A Isnansetyo, I Istiqomah… - Marine Biotechnology, 2022 - Springer
The marine bacterium Pseudoalteromonas xiamenensis STKMTI. 2 was isolated from a
mangrove soil sediment on Setokok Island, Batam, Indonesia. The genome of this bacterium …