Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial

S Mehta, L Burry, D Cook, D Fergusson, M Steinberg… - Jama, 2012 - jamanetwork.com
Context Protocolized sedation and daily sedation interruption are 2 strategies to minimize
sedation and reduce the duration of mechanical ventilation and intensive care unit (ICU) …

How to ventilate obstructive and asthmatic patients

A Demoule, L Brochard, M Dres, L Heunks… - Intensive care …, 2020 - Springer
Exacerbations are part of the natural history of chronic obstructive pulmonary disease and
asthma. Severe exacerbations can cause acute respiratory failure, which may ultimately …

Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study

T Pham, A Pesenti, G Bellani… - European …, 2021 - publications.ersnet.org
Background Current incidence and outcome of patients with acute hypoxaemic respiratory
failure requiring mechanical ventilation in the intensive care unit (ICU) are unknown …

The association of the COVID-19 pandemic and short-term outcomes of non-COVID-19 critically ill patients: an observational cohort study in Brazilian ICUs

FG Zampieri, LSL Bastos, M Soares, JI Salluh… - Intensive Care …, 2021 - Springer
Purpose To assess whether intensive care unit (ICU) outcomes for patients not affected by
coronavirus disease 2019 (COVID-19) worsened during the COVID-19 pandemic. Methods …

Long-term survival of mechanically ventilated patients with severe COVID-19: an observational cohort study

O Peñuelas, L del Campo-Albendea… - Annals of intensive …, 2021 - Springer
Background Information is lacking regarding long-term survival and predictive factors for
mortality in patients with acute hypoxemic respiratory failure due to coronavirus disease …

Effect of a lower vs higher positive end-expiratory pressure strategy on ventilator-free days in ICU patients without ARDS: a randomized clinical trial

Writing Committee and Steering Committee for the … - Jama, 2020 - jamanetwork.com
Importance It is uncertain whether invasive ventilation can use lower positive end-expiratory
pressure (PEEP) in critically ill patients without acute respiratory distress syndrome (ARDS) …

Metabolomic diferences between COVID-19 and H1N1 influenza induced ARDS

JA Lorente, N Nin, P Villa, D Vasco, AB Miguel-Coello… - Critical Care, 2021 - Springer
Background Acute respiratory distress syndrome (ARDS) is a type of respiratory failure
characterized by lung inflammation and pulmonary edema. Coronavirus disease 2019 …

In-hospital mortality, comorbidities, and costs of one million mechanically ventilated patients in Germany: a nationwide observational study before, during, and after the …

C Karagiannidis, F Krause, C Bentlage… - The Lancet Regional …, 2024 - thelancet.com
Background Even more than hospital care in general, intensive care and mechanical
ventilation capacities and its utilization in terms of rates, indications, ventilation types and …

Effect of different levels of PEEP on mortality in ICU patients without acute respiratory distress syndrome: systematic review and meta-analysis with trial sequential …

S Shao, H Kang, Z Qian, Y Wang, Z Tong - Journal of Critical Care, 2021 - Elsevier
Objective To determine whether higher positive end-expiratory pressure (PEEP) could
provide a survival advantage for patients without acute respiratory distress syndrome …

Evolution over time of ventilatory management and outcome of patients with neurologic disease

EE Tejerina, P Pelosi, C Robba, O Peñuelas… - Critical care …, 2021 - journals.lww.com
OBJECTIVES: To describe the changes in ventilator management over time in patients with
neurologic disease at ICU admission and to estimate factors associated with 28-day hospital …