C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis

S Huang, J Li, S Wu, Z Zheng, C Wang, H Li, L Zhao… - Oncogene, 2023 - nature.com
Colorectal cancer (CRC) is one of the most common malignant tumors in the gastrointestinal
tract, and has been attracted a great deal attention and extensive investigation due to its …

Clear cell renal cell carcinoma: immunological significance of alternative splicing signatures

J Zhang, H Jiang, D Rao, X Jin - Frontiers in Oncology, 2024 - frontiersin.org
Background Renal cell carcinoma (RCC) accounts for 90% of renal cancers, of which clear
cell carcinoma (ccRCC) is the most usual histological type. The process of alternative …

Molecular complex detection in protein interaction networks through reinforcement learning

MV Palukuri, RS Patil, EM Marcotte - BMC bioinformatics, 2023 - Springer
Background Proteins often assemble into higher-order complexes to perform their biological
functions. Such protein–protein interactions (PPI) are often experimentally measured for …

Machine learning methods for community detection in networks using known community information

MV Palukuri - 2022 - repositories.lib.utexas.edu
In a network, the problem of community detection refers to finding groups of nodes and
edges that form 'communities' relevant to the field, such as groups of people with common …