Extracellular vesicles (EVs), including exosomes, microvesicles, and oncosomes, are nano-
sized particles enclosed by a lipid bilayer. EVs are released by virtually all eukaryotic cells …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects
elderly people and constitutes a major source of disability worldwide. Notably, the …

In severe cases, Parkinson's disease causes uncontrolled movements known as motor
symptoms such as dystonia, rigidity, bradykinesia, and tremors. Parkinson's disease also …

This review gives an insight into the beginnings of dopamine transporter (DAT) imaging in
the early 1990s, focussing on single photon emission tomography (SPECT). The …

Highlights Imaging of the dopamine transporter (DAT)(in particular using 11C-or 18F-PE2I)
most reliably and precisely measures neurodegeneration of the dopaminergic system in …

The use of a diagnostic panel comprising multiple biomarkers has the potential to accurately
diagnose Parkinson's disease (PD). However, a panel consisting solely of plasma …

The acidic extracellular microenvironment has become an effective target for diagnosing
and treating tumors. A pH (low) insertion peptide (pHLIP) is a kind of peptide that can …

PREAMBLE The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is an
international scientific and professional organization founded in 1954 to promote the …

Neurodegenerative parkinsonisms affect mainly cognitive and motor functions and are
syndromes of overlapping symptoms and clinical manifestations such as tremor, rigidness …

Nanoscale contrast agents have emerged as a versatile platform in the field of biomedical
research, offering great potential for ultrasound imaging and therapy. Various kinds of …