• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Infective endocarditis (IE) is an inflammatory disease usually caused by bacteria entering
the bloodstream and settling in the heart lining valves or blood vessels. Despite modern …

Importance Practice guidelines often provide recommendations in which the strength of the
recommendation is dissociated from the quality of the evidence. Objective To create a …

Background: Streptococci frequently cause infective endocarditis (IE), yet the prevalence of
IE in patients with bloodstream infections (BSIs) caused by different streptococcal species is …

Enterococcus faecalis is a commensal bacterium commonly found in the human
gastrointestinal tract. However, in individuals with compromised immune systems, the …

In the late 1930s and early 1940s, it was discovered that the substitution on aromatic rings of
hydrogen atoms with chlorine yielded a novel chemistry of antimicrobials. However, within a …

Background Enterococcal bacteraemia (EB) is common, particularly in the nosocomial
setting, and its management poses a challenge for clinicians and microbiologists. Objectives …

Background Enterococcus faecalis infective endocarditis (EFIE) is characterized by a higher
frequency of relapses than other infective endocarditis. The role of the treatment on its …

Objectives: Outline the diseases caused by enterococci. Identify the mechanism of
resistance of enterococcus to commonly used antibiotics. Describe the various treatment …

Aims Little is known about the mortality for patients with infective endocarditis (IE) on a
nationwide scale, and previous studies have been conducted in selected cohorts from …