Precision medicine in fatty liver disease/non-alcoholic fatty liver disease

L Valenzuela-Vallejo, D Sanoudou… - Journal of Personalized …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …

What Is in a Name: from NAFLD to MAFLD and MASLD—Unraveling the Complexities and Implications

MM Ramírez-Mejía, N Méndez-Sánchez - Current Hepatology Reports, 2023 - Springer
Abstract Purpose of Review This review aims to examine the evolution of terminology,
diagnostic criteria, epidemiologic considerations, and clinical implications of the change …

[HTML][HTML] Prevalence and clinical outcomes in subtypes of metabolic associated fatty liver disease

KL Cheng, SW Wang, YM Cheng, TH Hsieh… - Journal of the Formosan …, 2024 - Elsevier
Background/purpose In 2020, metabolic Associated Fatty Liver Disease (MAFLD) was
proposed to replace non-alcoholic fatty liver disease (NAFLD) with new diagnostic criteria …

[HTML][HTML] FLAME: Training and Validating a Newly Conceived Model Incorporating Alpha-Glutathione-S-Transferase Serum Levels for Predicting Advanced Hepatic …

M Dallio, M Romeo, F Di Nardo, P Vaia… - International Journal of …, 2025 - mdpi.com
Alpha-Glutathione-S-transferase (alphaGST) is a liver enzyme whose serum levels increase
with the worsening of fibrosis in alcoholic and viral chronic hepatitis. Its usefulness in …

Design, synthesis, and biological evaluation of imidazo [4, 5-b] pyridine mitochondrial uncouplers for the treatment of metabolic dysfunction-associated steatohepatitis …

JM Salamoun, EL Krinos, MA Foutz, SR Hargett… - European Journal of …, 2024 - Elsevier
Small molecule mitochondrial uncouplers have gained traction for their potential therapeutic
use against metabolic dysfunction-associated steatohepatitis (MASH). Herein, we report a …