[HTML][HTML] Human Studies of Transcranial Ultrasound neuromodulation: A systematic review of effectiveness and safety

C Sarica, JF Nankoo, A Fomenko, TC Grippe… - Brain stimulation, 2022 - Elsevier
Background Transcranial ultrasound stimulation (TUS) is gaining traction as a safe and non-
invasive technique in human studies. There has been a rapid increase in TUS human …

Ultrasound as a versatile tool for short-and long-term improvement and monitoring of brain function

DG Blackmore, D Razansky, J Götz - Neuron, 2023 - cell.com
Treating the brain with focused ultrasound (FUS) at low intensities elicits diverse responses
in neurons, astroglia, and the extracellular matrix. In combination with intravenously injected …

Pilot study of focused ultrasound for drug‐resistant epilepsy

CC Lee, CC Chou, FJ Hsiao, YH Chen, CF Lin… - …, 2022 - Wiley Online Library
Objective The neuromodulatory effects of focused ultrasound (FUS) have been
demonstrated in animal epilepsy models; however, the safety and efficacy of FUS in humans …

Transcranial focused ultrasound neuromodulation: a review of the excitatory and inhibitory effects on brain activity in human and animals

T Zhang, N Pan, Y Wang, C Liu, S Hu - Frontiers in Human …, 2021 - frontiersin.org
Non-invasive neuromodulation technology is important for the treatment of brain diseases.
The effects of focused ultrasound on neuronal activity have been investigated since the …

Ultrasound neuromodulation as a new brain therapy

R Beisteiner, M Hallett, AM Lozano - Advanced Science, 2023 - Wiley Online Library
Within the last decade, ultrasound has been “rediscovered” as a technique for brain
therapies. Modern technologies allow focusing ultrasound through the human skull for …

Acoustic properties across the human skull

TS Riis, TD Webb, J Kubanek - Ultrasonics, 2022 - Elsevier
Transcranial ultrasound is emerging as a noninvasive tool for targeted treatments of brain
disorders. Transcranial ultrasound has been used for remotely mediated surgeries, transient …

Low intensity focused ultrasound for non-invasive and reversible deep brain neuromodulation—a paradigm shift in psychiatric research

AR Arulpragasam, M van't Wout-Frank… - Frontiers in …, 2022 - frontiersin.org
This article describes an emerging non-invasive neuromodulatory technology, called low
intensity focused ultrasound (LIFU). This technology is potentially paradigm shifting as it can …

Transcranial focused ultrasound stimulation of cortical and thalamic somatosensory areas in human

HC Kim, W Lee, DS Weisholtz, SS Yoo - PLoS One, 2023 - journals.plos.org
The effects of transcranial focused ultrasound (FUS) stimulation of the primary
somatosensory cortex and its thalamic projection (ie, ventral posterolateral nucleus) on the …

Low-intensity ultrasound restores long-term potentiation and memory in senescent mice through pleiotropic mechanisms including NMDAR signaling

DG Blackmore, F Turpin, T Palliyaguru, HT Evans… - Molecular …, 2021 - nature.com
Advanced physiological aging is associated with impaired cognitive performance and the
inability to induce long-term potentiation (LTP), an electrophysiological correlate of memory …

Device for multifocal delivery of ultrasound into deep brain regions in humans

T Riis, D Feldman, A Losser, B Mickey… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Low-intensity focused ultrasound provides the means to noninvasively stimulate or release
drugs in specified deep brain targets. However, successful clinical translations require …