MicroRNAs (miRNA) are a class of endogenous regulatory RNA molecules 21–24
nucleotides in length that modulate gene expression at the post-transcriptional level via …

Insecticide resistance is a major obstacle to control of Anopheles malaria mosquitoes in sub-
Saharan Africa and requires an improved understanding of the underlying mechanisms …

Mosquitoes are vectors for multiple infectious human diseases and use a variety of sensory
cues (olfactory, temperature, humidity and visual) to locate a human host. A comprehensive …

Resistance in Anopheles gambiae to members of all 4 major classes (pyrethroids,
carbamates, organochlorines, and organophosphates) of public health insecticides limits …

Mosquito-transmitted diseases, including malaria and dengue, are a major threat to human
health around the globe, affecting millions each year. A diverse array of next-generation …

Transgenesis is an essential tool to investigate gene function and to introduce desired
characters in laboratory organisms. Setting-up transgenesis in non-model organisms is …

Drosophila melanogaster olfactory neurons have long been thought to express only one
chemosensory receptor gene family. There are two main olfactory receptor gene families in …

Mosquito transgenesis and gene-drive technologies provide the basis for developing
promising new tools for vector-borne disease prevention by either suppressing wild …

Reduction in malaria clinical cases is strongly dependent on the ability to prevent Anopheles
infectious bites. Vector control strategies using long-lasting insecticidal nets and indoor …

Highlights•Functional genomics have been key to deciphering mechanisms of insecticide
resistance.•The model organism D. melanogaster has played a central role in these …