[HTML][HTML] Recent developments and applications of the MMPBSA method

C Wang, DA Greene, L Xiao, R Qi… - Frontiers in molecular …, 2018 - frontiersin.org
The Molecular Mechanics Poisson-Boltzmann Surface Area (MMPBSA) approach has been
widely applied as an efficient and reliable free energy simulation method to model molecular …

Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies

AC Marques, PJ Costa, S Velho, MH Amaral - Journal of controlled release, 2020 - Elsevier
Standard cancer therapies sometimes fail to deliver chemotherapeutic drugs to tumor cells
in a safe and effective manner. Nanotechnology takes the lead in providing new therapeutic …

Synthesis, assembly, and applications of hybrid nanostructures for biosensing

S Zhang, R Geryak, J Geldmeier, S Kim… - Chemical …, 2017 - ACS Publications
The robust, sensitive, and selective detection of targeted biomolecules in their native
environment by prospective nanostructures holds much promise for real-time, accurate, and …

Aptamers from random sequence space: Accomplishments, gaps and future considerations

S Qian, D Chang, S He, Y Li - Analytica Chimica Acta, 2022 - Elsevier
Aptamers are molecular recognition elements made of nucleic acids. Diverse synthetic
aptamers have been discovered in a large number of SELEX experiments since 1990. This …

Synthetic mimics of biotin/(strept) avidin

W Liu, SK Samanta, BD Smith, L Isaacs - Chemical Society Reviews, 2017 - pubs.rsc.org
Biotin/(strept) avidin self-assembly is a powerful platform for nanoscale fabrication and
capture with many different applications in science, medicine, and nanotechnology …

Transition metal catalysis in living cells: progress, challenges, and novel supramolecular solutions

CC James, B de Bruin, JNH Reek - Angewandte Chemie, 2023 - Wiley Online Library
The importance of transition metal catalysis is exemplified by its wide range of applications,
for example in the synthesis of chemicals, natural products, and pharmaceuticals. However …

Cytosolic Protein Delivery Using Modular Biotin–Streptavidin Assembly of Nanocomposites

DC Luther, YW Lee, H Nagaraj, V Clark, T Jeon… - ACS …, 2022 - ACS Publications
Current strategies for the delivery of proteins into cells face general challenges of
endosomal entrapment and concomitant degradation of protein cargo. Efficient delivery …

Direction matters: Monovalent streptavidin/biotin complex under load

SM Sedlak, LC Schendel, MCR Melo, DA Pippig… - Nano …, 2018 - ACS Publications
Novel site-specific attachment strategies combined with improvements of computational
resources enable new insights into the mechanics of the monovalent biotin/streptavidin …

[HTML][HTML] Highly sensitive detection of dengue biomarker using streptavidin-conjugated quantum dots

L Tran, S Park - Scientific Reports, 2021 - nature.com
A highly sensitive immunosensor using streptavidin-conjugated quantum dots (QDs/SA) was
developed to detect dengue biomarker of non-structural protein 1 (NS1) at very low …

Impact of silane monolayers on the adsorption of streptavidin on silica and its subsequent interactions with biotin: molecular dynamics and steered molecular …

S Lecot, Y Chevolot, M Phaner-Goutorbe… - The Journal of …, 2020 - ACS Publications
Protein adsorption on surfaces is used in analytical tools as an immobilization mean to trap
the analyte to be detected. However, protein adsorption can lead to a conformational …