A reduction in CD90 (THY-1) expression results in increased differentiation of mesenchymal stromal cells

DA Moraes, TT Sibov, LF Pavon, PQ Alvim… - Stem cell research & …, 2016 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) are multipotent progenitor cells
used in several cell therapies. MSCs are characterized by the expression of CD73, CD90 …

On the role of platelet-generated amyloid beta peptides in certain amyloidosis health complications

M Inyushin, A Zayas-Santiago, L Rojas… - Frontiers in …, 2020 - frontiersin.org
As do many other immunity-related blood cells, platelets release antimicrobial peptides that
kill bacteria, fungi, and even certain viruses. Here we review the literature suggesting that …

Thy-1 (CD90), integrins and syndecan 4 are key regulators of skin wound healing

LA Pérez, L Leyton, A Valdivia - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Acute skin wound healing is a multistage process consisting of a plethora of tightly regulated
signaling events in specialized cells. The Thy-1 (CD90) glycoprotein interacts with integrins …

Chemotherapy-induced cognitive impairment is associated with cytokine dysregulation and disruptions in neuroplasticity

DD Shi, YH Huang, CSW Lai, CM Dong, LC Ho… - Molecular …, 2019 - Springer
Chemotherapy-induced cognitive impairment, often referred to as “chemobrain,” is a
common side effect. In this study, mice received three intraperitoneal injections of a …

Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins

AM Cheatham, NR Sharma… - Journal of Cell Biology, 2023 - rupress.org
In mammalian cells, misfolded glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-
APs) are cleared out of the ER to the Golgi via a constitutive and a stress-inducible pathway …

[HTML][HTML] Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma

RG Marangoni, P Datta, A Paine, S Duemmel… - JCI insight, 2022 - ncbi.nlm.nih.gov
Abstract Thy-1 (CD90) is a well-known marker of fibroblasts implicated in organ fibrosis, but
its contribution to skin fibrosis remains unknown. We examined Thy-1 expression in …

The GPI-anchored protein Thy-1/CD90 promotes wound healing upon injury to the skin by enhancing skin perfusion

LA Pérez, J León, J López, D Rojas, M Reyes… - International Journal of …, 2022 - mdpi.com
Wound healing is a highly regulated multi-step process that involves a plethora of signals.
Blood perfusion is crucial in wound healing and abnormalities in the formation of new blood …

[HTML][HTML] Neural stem cells from mouse strain Thy1 YFP-16 are a valuable tool to monitor and evaluate neuronal differentiation and morphology

I Alić, N Kosi, K Kapuralin, D Gorup, S Gajović… - Neuroscience …, 2016 - Elsevier
To analyse events following transplantation of stem cells in the brain robust tools for tracing
stem cells are required. Here we took advantage of the mouse strain B6. Cg-Tg (Thy1-YFP) …

Modulating stemness of mesenchymal stem cells from exfoliated deciduous and permanent teeth by IL‐17 and bFGF

A Jauković, T Kukolj, D Trivanović… - Journal of cellular …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been identified within dental pulp tissues of exfoliated
deciduous (SHEDs) and permanent (DPSCs) teeth. Although differences in their proliferative …

Thy1-YFP: an effective tool for single cell tracing from neuronal progenitors to mature functionally active neurons

A Plećaš, K Kapuralin, L Grandverger, D Mitrečić… - Cell Death …, 2025 - nature.com
The differentiation of mouse neurons is a complex process involving cell maturation and
branching, occurring during both, embryonic development and differentiation in vitro. To …