Recent progress in the chemistry of β-aminoketones

MM Hammouda, KM Elattar - RSC advances, 2022 - pubs.rsc.org
The β-aminoketone moiety has been found to be the basic skeleton of several drugs such as
the amine salts “tolperisone (vasodilation)” and “oxyfedrine (therapeutic coronary disease)” …

Synthesis of hemilabile cyclic (alkyl)(amino) carbenes (CAACs) and applications in organometallic chemistry

J Chu, D Munz, R Jazzar, M Melaimi… - Journal of the American …, 2016 - ACS Publications
A versatile methodology, involving readily available starting materials, allows for the
synthesis of stable hemilabile bidentate cyclic (alkyl)(amino) carbenes (CAACs) featuring …

Catalysis and regioselectivity in hydrofunctionalization reactions of unsaturated carbon bonds. Part II. Hydroamination

IP Beletskaya, C Naájera, M Yus - Russian Chemical Reviews, 2020 - iopscience.iop.org
This review continues consideration of the regioselectivity problem in the catalyzed
hydrofunctionalization of unsaturated organic compounds and addresses hydroamination of …

Cobalt-catalyzed Markovnikov selective sequential hydrogenation/hydrohydrazidation of aliphatic terminal alkynes

J Chen, X Shen, Z Lu - Journal of the American Chemical Society, 2020 - ACS Publications
Here, we reported for the first time a mechanistically distinctive cobalt-catalyzed
Markovnikov-type sequential semihydrogenation/hydrohydrazidation of aliphatic terminal …

Copper-catalyzed hydroamination of terminal allenes

R Blieck, J Bahri, M Taillefer, F Monnier - Organic letters, 2016 - ACS Publications
The ligand-free copper-catalyzed hydroamination of allenes has been accomplished in the
presence of cyclic secondary amines or anilines derivatives. This novel methodology …

Copper-catalyzed hydroamination of allenes: from mechanistic understanding to methodology development

LA Perego, R Blieck, A Groué, F Monnier… - Acs …, 2017 - ACS Publications
Experimental and theoretical mechanistic studies on the Cu (OTf) 2-catalyzed
hydroamination reaction of terminal allenes with secondary amines reveal that in situ …

Regiospecific Hydroamination of Unsymmetrical Electron‐Rich and Electron‐Poor Alkynes with Anilines Catalyzed by Gold (I) Immobilized in MCM‐41

D Liu, Q Nie, R Zhang, M Cai - Advanced Synthesis & Catalysis, 2018 - Wiley Online Library
The first heterogeneous gold (I)‐catalyzed regiospecific hydroamination of ynamides and
propiolic acid derivatives with anilines has been achieved by using a diphenylphosphine …

N, N′-GEKSAMETILEN BIS-[(O-, M-KREZOLILO)-KARBAMAT] LARNING O 'TKIR TOKSIKLIGINI O 'RGANISH

M Abdulhamid, M Eldor, S Feruz… - Universal journal of …, 2023 - humoscience.com
The article presents the results of an in silico study of the acute toxicity of LD50, ecotoxicity
and organ-specific carcinogenic biological activity of N, N'-hexamethylene-bis-[(o, m …

Commercial supported gold nanoparticles catalyzed alkyne hydroamination and indole synthesis

S Liang, L Hammond, B Xu… - Advanced Synthesis & …, 2016 - Wiley Online Library
Commercial gold nanoparticles supported on titanium dioxide (TiO2) were found to be a
highly efficient catalyst for alkyne hydroamination. Terminal alkynes could easily undergo …

Copper-catalyzed C (sp)–H aryl amination enables modular synthesis of quinolines and 2-quinolinones

Y Gao, H Li, S Yang, Y Huo, Q Chen, X Li… - Science China …, 2024 - Springer
Herein, we disclose a novel copper-catalyzed C (sp)–H aryl amination of terminal alkynes
with anthranils, enabling the rapid generation of highly reactive secondary N-aryl ynamines …