Publisher Summary This chapter discusses the structure and organization of mammalian,
highly repeated sequences at the molecular level. There is a description of tandemly …

The ability of eukaryotic organisms of the same genotype to vary in developmental pattern or
in phenotype according to varying environmental conditions is frequently associated with …

Most quantitative traits in most populations exhibit heritable genetic variation. Lande
proposed that high levels of heritable variation may be maintained by mutation in the face of …

DNA replication in mammals is temporally bimodal." Housekeeping" genes, which are active
in all cells, replicate during the first half of the S phase of cell growth. Tissue-specific genes …

Mouse genome contains two major families of short interspersed repeats in more than 105
copies scattered throughout the whole genome. They are referred to as B1 and B2 …

We investigated the genomic distribution of mouse and human repeated sequences by
assessing their relative amounts in the four major components into which these genomes …

This chapter emphasises on the studies that have focused on understanding the mechanism
of L1 retrotransposition, which were conducted since the publication of Mobile DNA in 1989 …

Mobile genetic elements were discovered by McClintock while analysing unstable mutations
in maize. The structural and functional studies of such elements became possible after their …

Reverse transcription intermediate forms (minus and plus strong-stop DNA) are detected in
Drosophila melanogaster cultured cells for mobile dispersed genetic elements mdgl, mdg3 …

We have isolated clones containing the gene for tumor necrosis factor (TNF-alpha) from a
mouse genomic library. Four out of five clones containing the TNF-alpha gene also …