Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic
instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration …

The core promoter (CP) of the viral genome plays an important role for hepatitis B virus
(HBV) replication as it directs initiation of transcription for the synthesis of both the precore …

Of 350 million people worldwide are chronically infected with hepatitis B virus (HBV) and are
at risk of developing cirrhosis and hepatocellular carcinoma (HCC) later in life. HBV is the …

Background and objective Precore (PC) variant (G1896A) and basal core promoter (BCP)
variant (A1762T/G1764A) of HBV are associated with risk of hepatocellular carcinoma in …

Infection with hepatitis B virus (HBV) is a major risk factor for hepatocellular carcinoma
(HCC) in developed countries. Epidemiological reports indicate that the incidence of HBV …

Hepatitis B virus (HBV) is a global health problem that can lead to cirrhosis and
hepatocellular carcinoma (HCC). Although HBV vaccination has reduced the prevalence Of …

Despite the availability of an effective vaccine, hepatitis B virus (HBV) infection remains a
major health problem, with more than 350 million chronically infected people worldwide and …

Chronic hepatitis B virus (HBV) infection is one of the most common causes of
hepatocellular carcinoma (HCC), a malignant tumor with high mortality worldwide. One …

Chronic hepatitis B is a worldwide disease, with significant burden on health care systems.
While universal vaccination programs have led to an overall decrease in incidence of …

Liver fibrosis is a wound-healing response to a wide spectrum of chronic liver injuries. It is
characterized by loss of hepatocytes and alteration in hepatic architecture following an …