Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

Epilepsy can be both a primary pathology and a secondary effect of many neurological
conditions. Many papers show that neuroinflammation is a product of epilepsy, and that in …

In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic
cannabinoids have received growing interest as treatment options in neurodegenerative …

The combination of immune checkpoint blockade (ICB) with chemotherapy significantly
improves clinical benefit of cancer treatment. Since chemotherapy is often associated with …

Thirty years ago, the discovery of a cannabinoid (CB) receptor that interacts with the
psychoactive compound in Cannabis led to the identification of anandamide, an …

Introduction: The endocannabinoid (eCB) system plays a key role in maintaining
homeostasis, including the regulation of metabolism and stress responses. Chronic stress …

As the major nonpsychotropic constituent of Cannabis sativa, cannabidiol (CBD) is regarded
as one of the most promising therapeutic agents due to its proven effectiveness in clinical …

Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis Sativa, has
garnered increasing attention for its diverse therapeutic potential. This comprehensive …

The review discusses molecular and cellular mechanisms common to the temporal lobe
epileptogenesis/epilepsy and depressive disorders. Comorbid temporal lobe epilepsy and …