Local anesthetics (LAs) are medications which can provide analgesia in distinct body
regions through the blockade of voltage-gated sodium channels. Besides pain …

Over the last few decades, there has been a growing interest in developing innovative drug
delivery approaches that can assist drug release to attain the vital extent of therapeutic …

The work reports the results of an analysis of the lidocaine molecule conformational
behavior in a supercritical carbon dioxide medium. Based on the nuclear Overhauser effect …

Background Most patients with bacterial infections suffer from fever and various pains that
require complex treatments with antibiotics, antipyretics, and analgaesics. The most …

The potential role of non-antibiotic medicinal products in the treatment of multidrug-resistant
Gram-negative bacteria has recently been investigated. It is highly likely that the presence of …

Hancı V, Hakimoğlu S, Özaçmak H, Bektaş S, Özaçmak HS, Özdamar ŞO, Yurtlu S, Turan IÖ–
Comparison of the Effects of Bupivacaine, Lidocaine, and Tramadol Infiltration on Wound …

Topical anesthetics are commonly used in oral & maxillofacial surgery to control pain in the
oral cavity mucosa before local anesthetic injection. These anesthetic agents come in many …

After the introduction of cocaine to the medical practice, local anaesthetics (LA) became
essential in pain control. LA infiltration along the incision may be used to provide surgical …

Mechanochemistry has been recognized as an optimal route for the synthesis of ionic liquids
incorporating active pharmaceutical ingredients (API-ILs) as it eliminates the need for large …

Tuning of physicochemical properties of ionic liquids and crystalline materials is a challenge
that opens up unlimited possibilities for expanding applications and controlling biological …