Photoacoustically guided wavefront shaping for enhanced optical focusing in scattering media

P Lai, L Wang, JW Tay, LV Wang - Nature photonics, 2015 - nature.com
Non-invasively focusing light into strongly scattering media, such as biological tissue, is
highly desirable but challenging. Recently, ultrasonically guided wavefront-shaping …

Deep-tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light

YM Wang, B Judkewitz, CA DiMarzio, C Yang - Nature communications, 2012 - nature.com
Fluorescence imaging is one of the most important research tools in biomedical sciences.
However, scattering of light severely impedes imaging of thick biological samples beyond …

Optical focusing deep inside dynamic scattering media with near-infrared time-reversed ultrasonically encoded (TRUE) light

Y Liu, P Lai, C Ma, X Xu, AA Grabar, LV Wang - Nature communications, 2015 - nature.com
Focusing light deep inside living tissue has not been achieved despite its promise to play a
central role in biomedical imaging, optical manipulation and therapy. To address this …

Speckle-scale focusing in the diffusive regime with time reversal of variance-encoded light (TROVE)

B Judkewitz, YM Wang, R Horstmeyer, A Mathy… - Nature …, 2013 - nature.com
Focusing of light in the diffusive regime inside scattering media has long been considered
impossible. Recently, this limitation has been overcome with time reversal of ultrasound …

Review of current methods of acousto-optical tomography for biomedical applications

J Gunther, S Andersson-Engels - Frontiers of Optoelectronics, 2017 - Springer
The field of acousto-optical tomography (AOT) for medical applications began in the 1990s
and has since developed multiple techniques for the detection of ultrasound-modulated …

Breaking acoustic limit of optical focusing using photoacoustic‐guided wavefront shaping

R Gao, Z Xu, L Song, C Liu - Laser & Photonics Reviews, 2021 - Wiley Online Library
Optical wavefront shaping (WFS) has been demonstrated as a powerful tool for focusing
light in opaque scattering media. Photoacoustic (PA)‐guided WFS, in particular, has raised a …

Perspective: Wavefront shaping techniques for controlling multiple light scattering in biological tissues: Toward in vivo applications

JH Park, Z Yu, KR Lee, P Lai, YK Park - APL photonics, 2018 - pubs.aip.org
Light scattering is a fundamental physical phenomenon and also plays critical roles in
optical imaging. To optically visualize an object, waves scattered from individual positions in …

Time-reversed magnetically controlled perturbation (TRMCP) optical focusing inside scattering media

Z Yu, J Huangfu, F Zhao, M Xia, X Wu, X Niu, D Li… - Scientific reports, 2018 - nature.com
Manipulating and focusing light deep inside biological tissue and tissue-like complex media
has been desired for long yet considered challenging. One feasible strategy is through …

Implementation of digital optical phase conjugation with embedded calibration and phase rectification

Z Yu, M Xia, H Li, T Zhong, F Zhao, H Deng, Z Li, D Li… - Scientific reports, 2019 - nature.com
Focused and controllable optical delivery beyond the optical diffusion limit in biological
tissue has been desired for long yet considered challenging. Digital optical phase …

Edge enhancement through scattering media enabled by optical wavefront shaping

Z Li, Z Yu, H Hui, H Li, T Zhong, H Liu, P Lai - Photonics Research, 2020 - opg.optica.org
Edge enhancement is a fundamental and important topic in imaging and image processing,
as perception of edge is one of the keys to identify and comprehend the contents of an …