Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium
that colonizes the intestinal mucosa of humans and rodents. Metagenomic data have shown …

Obesity is caused by a long-term difference between energy intake and expenditure—an
imbalance that is seemingly easily restored by increasing exercise and reducing caloric …

The human gut microbiota has gained interest as an environmental factor that may
contribute to health or disease. The development of next-generation probiotics is a …

Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …

Background Microbiome-gut-brain axis may be involved in the progression of age-related
cognitive impairment and relevant brain structure changes, but evidence from large human …

Inulin, a soluble dietary fiber, is widely found in more than 36 000 plant species as a reserve
polysaccharide. The primary sources of inulin, include Jerusalem artichoke, chicory, onion …

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death worldwide. It involves the complex interactions between genetic …

Inulin consumption in both humans and animal models is recognized for its prebiotic action
with the most consistent change that lies in enhancing the growth and functionality of …

Overweight and obesity are associated with several cardiometabolic risk factors, including
insulin resistance, type 2 diabetes, low-grade inflammation and liver diseases. The gut …

Accumulating evidence indicates that the gut microbiome is an important regulator of body
weight, glucose and lipid metabolism, and inflammatory processes, and may thereby play a …