The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

Emerging and reemerging infectious diseases: global trends and new strategies for their prevention and control

S Wang, W Li, Z Wang, W Yang, E Li, X Xia… - … and Targeted Therapy, 2024 - nature.com
To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …

Zika virus enhances monocyte adhesion and transmigration favoring viral dissemination to neural cells

NV Ayala-Nunez, G Follain, F Delalande… - Nature …, 2019 - nature.com
Zika virus (ZIKV) invades and persists in the central nervous system (CNS), causing severe
neurological diseases. However the virus journey, from the bloodstream to tissues through a …

Acute and chronic neurological consequences of early-life Zika virus infection in mice

I Nem de Oliveira Souza, PS Frost, JV França… - Science translational …, 2018 - science.org
Although congenital Zika virus (ZIKV) exposure has been associated with microcephaly and
other neurodevelopmental disorders, long-term consequences of perinatal infection are …

Pathophysiology and mechanisms of Zika virus infection in the nervous system

KM Christian, H Song, G Ming - Annual review of neuroscience, 2019 - annualreviews.org
In 2015, public awareness of Zika virus (ZIKV) rose in response to alarming statistics of
infants with microcephaly being born to women who were infected with the virus during …

A combination of two human monoclonal antibodies prevents Zika virus escape mutations in non-human primates

JR Keeffe, KKA Van Rompay, PC Olsen, Q Wang… - Cell reports, 2018 - cell.com
Zika virus (ZIKV) causes severe neurologic complications and fetal aberrations. Vaccine
development is hindered by potential safety concerns due to antibody cross-reactivity with …

Zika virus and the nonmicrocephalic fetus: why we should still worry

CL Walker, MTE Little, JA Roby, B Armistead… - American journal of …, 2019 - Elsevier
Zika virus is a mosquito-transmitted flavivirus and was first linked to congenital microcephaly
caused by a large outbreak in northeastern Brazil. Although the Zika virus epidemic is now …

Long-term persistence of infectious Zika virus: inflammation and behavioral sequela in mice

DDC Ireland, M Manangeeswaran… - Plos …, 2020 - journals.plos.org
The neurodevelopmental defects associated with ZIKV infections early in pregnancy are well
documented, however the potential defects and long-term consequences associated with …

Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques

J Raper, Z Kovacs-Balint, M Mavigner… - Nature …, 2020 - nature.com
Zika virus (ZIKV) infection has a profound impact on the fetal nervous system. The postnatal
period is also a time of rapid brain growth, and it is important to understand the potential …

Nonhuman primate models of Zika virus infection and disease during pregnancy

NN Haese, VHJ Roberts, A Chen, DN Streblow… - Viruses, 2021 - mdpi.com
Since the explosive outbreak of Zika virus in Brazil and South/Central America in 2015–
2016, the frequency of infections has subsided, but Zika virus remains present in this region …