Harnessing the potential of miRNAs in malaria diagnostic and prevention

H Gupta, SC Wassmer - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Despite encouraging progress over the past decade, malaria remains a major global health
challenge. Its severe form accounts for the majority of malaria-related deaths, and early …

[HTML][HTML] Diagnosis of cerebral malaria: Tools to reduce Plasmodium falciparum associated mortality

P Muppidi, E Wright, SC Wassmer… - Frontiers in cellular and …, 2023 - frontiersin.org
Cerebral malaria (CM) is a major cause of mortality in Plasmodium falciparum (Pf) infection
and is associated with the sequestration of parasitised erythrocytes in the microvasculature …

TNF-α (g.−308 G > A) and ADIPOQ (g. + 45 T > G) Gene Polymorphisms in Type 2 Diabetes and Microvascular Complications in the Region of Punjab …

R Sikka, P Raina, K Matharoo, K Bandesh… - Current eye …, 2014 - Taylor & Francis
Aims: The present study aims to examine the association of tumor necrosis factor-α (TNF-α)
g.− 308 G> A and adiponectin (ADIPOQ) g.+ 45 T> G gene polymorphisms in type 2 …

Genetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum

H Gupta, S Chaudhari, A Rai, S Bhat, PK Sahu… - PLoS …, 2017 - journals.plos.org
Multiple mechanisms such as genetic and epigenetic variations within a key gene may play
a role in malarial susceptibility and response to anti-malarial drugs in the population. ABCB1 …

Overview of human genetic susceptibility to malaria: From parasitemia control to severe disease

S Marquet - Infection, Genetics and Evolution, 2018 - Elsevier
Malaria is a life-threatening blood disease caused by the protozoan Plasmodium. Infection
may lead to several different patterns of symptoms in the host: asymptomatic state …

Host genetic variations in glutathione-S-transferases, superoxide dismutases and catalase genes influence susceptibility to malaria infection in an Indian population

RC Fernandes, M Hasan, H Gupta, K Geetha… - Molecular Genetics and …, 2015 - Springer
Antioxidant enzymes can contribute to disease susceptibility or determine response to
therapy in individuals with malaria. Genetic variations due to polymorphisms in host genes …

Cerebral malaria in a man with Plasmodium vivax mono-infection: a case report

H Gupta, P Dhunputh, AN Bhatt… - Tropical …, 2016 - journals.sagepub.com
Cerebral malaria (CM) is a diffuse encephalopathy associated with coma and seizures
commonly caused by Plasmodium falciparum (P. falciparum) in children with severe malaria …

Unravelling the Influence of Host Genetic Factors on Malaria Susceptibility in Asian Populations

A Gupta, M Skjefte, P Muppidi, R Sikka, M Pandey… - Acta Tropica, 2023 - Elsevier
Malaria is a deadly blood-borne disease caused by a Plasmodium parasite. Infection results
in various forms of malaria, including an asymptomatic state, uncomplicated disease, or …

Plasmodium vivax infection causes acute respiratory distress syndrome: a case report

H Gupta, MP Afsal, SM Shetty, K Satyamoorthy… - The Journal of Infection …, 2015 - jidc.org
Plasmodium falciparum (Pf) is associated with numerous complications and high mortality,
whereas Plasmodium vivax (Pv) infection is generally considered to be benign. However …

Categorical complexities of Plasmodium falciparum malaria in individuals is associated with genetic variations in ADORA2A and GRK5 genes

H Gupta, A Jain, AV Saadi, TG Vasudevan… - Infection, Genetics and …, 2015 - Elsevier
In the erythrocytes, malaria parasite entry and infection is mediated through complex
membrane sorting and signaling processes. We investigated the effects of single-locus and …