The blood compatibility challenge. Part 4: Surface modification for hemocompatible materials: Passive and active approaches to guide blood-material interactions

MF Maitz, MCL Martins, N Grabow, C Matschegewski… - Acta biomaterialia, 2019 - Elsevier
Biomedical devices in the blood flow disturb the fine-tuned balance of pro-and anti-
coagulant factors in blood and vessel wall. Numerous technologies have been suggested to …

In vitro thrombogenicity testing of biomaterials

S Braune, RA Latour, M Reinthaler… - Advanced …, 2019 - Wiley Online Library
The short‐and long‐term thrombogenicity of implant materials is still unpredictable, which is
a significant challenge for the treatment of cardiovascular diseases. A knowledge‐based …

Biomimetic modification of poly (vinyl alcohol): Encouraging endothelialization and preventing thrombosis with antiplatelet monotherapy

DEJ Anderson, KP Truong, MW Hagen, EKF Yim… - Acta biomaterialia, 2019 - Elsevier
Abstract Poly (vinyl alcohol)(PVA) has shown promise as a biomaterial for cardiovascular
application. However, its antifouling properties prevent in vivo endothelialization. This work …

[HTML][HTML] Anti-fouling coatings for blood-contacting devices

S Yao, H Yan, S Tian, R Luo, Y Zhao, J Wang - Smart Materials in Medicine, 2024 - Elsevier
Blood-contacting medical devices, such as vascular stents, intravascular catheters, and
artificial heart valves, frequently encounter complications in clinical practice, including …

Hemocompatibility of super-repellent surfaces: current and future

S Movafaghi, W Wang, DL Bark, LP Dasi, KC Popat… - Materials …, 2019 - pubs.rsc.org
Virtually all blood-contacting medical implants and devices initiate immunological events in
the form of thrombosis and inflammation. Typically, patients receiving such implants are also …

Predicting the in vivo performance of cardiovascular biomaterials: current approaches in vitro evaluation of blood-biomaterial interactions

A Strohbach, R Busch - International Journal of Molecular Sciences, 2021 - mdpi.com
The therapeutic efficacy of a cardiovascular device after implantation is highly dependent on
the host-initiated complement and coagulation cascade. Both can eventually trigger …

BloodSurf 2017: News from the blood-biomaterial frontier

I Sotiri, M Robichaud, D Lee, S Braune, M Gorbet… - Acta Biomaterialia, 2019 - Elsevier
From stents and large-diameter vascular grafts, to mechanical heart valves and blood
pumps, blood-contacting devices are enjoying significant clinical success owing to the …

Bionic structure and blood compatibility of highly oriented homo-epitaxially crystallized poly (l-lactic acid)

W Yang, T Wu, Y Chen, Q Huang, J Ao, M Ming… - International Journal of …, 2023 - Elsevier
A highly oriented poly (l-lactic acid)(PLLA), with a blood vessel-like biomimetic structure,
was fabricated using solid-phase hot drawing technology and homo-epitaxial crystallization …

EndOxy: mid‐term stability and shear stress resistance of endothelial cells on PDMS gas exchange membranes

A Hellmann, S Klein, F Hesselmann… - Artificial …, 2020 - Wiley Online Library
Endothelialized oxygenator devices (EndOxy) with a physiological, nonthrombogenic, and
anti‐inflammatory surface offer the potential to overcome current shortcomings of …

Collagen type-IV Langmuir and Langmuir–Schäfer layers as model biointerfaces to direct stem cell adhesion

T Bhuvanesh, R Machatschek, L Lysyakova… - Biomedical …, 2019 - iopscience.iop.org
In biomaterial development, the design of material surfaces that mimic the extra-cellular
matrix (ECM) in order to achieve favorable cellular instruction is rather challenging …