Chronic stress, cognitive functioning and mental health

MF Marin, C Lord, J Andrews, RP Juster, S Sindi… - Neurobiology of learning …, 2011 - Elsevier
This review aims to discuss the evidence supporting the link between chronic stress,
cognitive function and mental health. Over the years, the associations between these …

Gene–environment interaction in major depression: focus on experience-dependent biological systems

N Lopizzo, L Bocchio Chiavetto, N Cattane… - Frontiers in …, 2015 - frontiersin.org
Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple
and partially overlapping sets of susceptibility genes interact each other and with the …

Poor replication of candidate genes for major depressive disorder using genome-wide association data

FJ Bosker, CA Hartman, IM Nolte, BP Prins… - Molecular …, 2011 - nature.com
Abstract Data from the Genetic Association Information Network (GAIN) genome-wide
association study (GWAS) in major depressive disorder (MDD) were used to explore …

Association of the 5-HTTLPR genotype and unipolar depression: a meta-analysis

H Clarke, J Flint, AS Attwood, MR Munafo - Psychological medicine, 2010 - cambridge.org
BackgroundWe sought to ascertain the strength of evidence for association between the 5-
HTTLPR polymorphism and unipolar depression. MethodWe applied meta-analytic …

Multichannel weighted speech classification system for prediction of major depression in adolescents

KEB Ooi, M Lech, NB Allen - IEEE Transactions on Biomedical …, 2012 - ieeexplore.ieee.org
Early identification of adolescents at high imminent risk for clinical depression could
significantly reduce the burden of the disease. This study demonstrated that acoustic speech …

[HTML][HTML] Platelets and depression in cardiovascular disease: a brief review of the current literature

MS Williams - World journal of psychiatry, 2012 - ncbi.nlm.nih.gov
Major depression is an independent risk factor for cardiovascular mortality and morbidity.
The exact mechanisms linking depression and increased cardiovascular risk remain poorly …

Association between major depressive disorder and a functional polymorphism of the 5-hydroxytryptamine (serotonin) transporter gene: a meta-analysis

C Kiyohara, K Yoshimasu - Psychiatric genetics, 2010 - journals.lww.com
Objectives A functional polymorphism in the promoter region of the 5-hydroxytryptamine
(serotonin) transporter (5-HTT) gene, termed 5-HTTLPR, alters transcription of the 5-HTT …

Associations of 5HTTLPR polymorphism with major depressive disorder and alcohol dependence: A systematic review and meta-analysis

KZ Oo, YK Aung, MA Jenkins… - Australian & New …, 2016 - journals.sagepub.com
Objective: The neurotransmitter serotonin is understood to control mood and drug response.
Carrying a genetic variant in the serotonin transporter gene (5HTT) may increase the risk of …

CYP2D6 variation, behaviour and psychopathology: implications for pharmacogenomics‐guided clinical trials

EM Peñas‐LLedó, A LLerena - British journal of clinical …, 2014 - Wiley Online Library
Individual and population differences in polymorphic cytochrome P 450 enzyme function
have been known for decades. The biological significance of these differences has now …

Investigation of the serotonergic activity and the serotonin content in serum and platelet, and the possible role of the serotonin transporter in patients with depression

J Obermanns, V Flasbeck, S Steinmann, G Juckel… - Behavioral …, 2022 - mdpi.com
According to the monoamine hypothesis, the development of depression is associated with
dysfunctions of the serotonergic system. Alterations in the serotonin transporter gene (5 …