International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis

X Chen, AS Tsvetkov, HM Shen, C Isidoro… - Autophagy, 2024 - Taylor & Francis
Macroautophagy/autophagy is a complex degradation process with a dual role in cell death
that is influenced by the cell types that are involved and the stressors they are exposed to …

[HTML][HTML] Crosstalk between ferroptosis and cuproptosis: From mechanism to potential clinical application

N Liu, M Chen - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Ferroptosis and cuproptosis, regulated forms of cell death resulting from metal ion
accumulation, are closely related in terms of occurrence, cell metabolism, signaling …

The role of ferroptosis and its mechanism in ischemic stroke

X Hu, Y Bao, M Li, W Zhang, C Chen - Experimental Neurology, 2023 - Elsevier
Ischemic stroke is an acute cerebrovascular disease with a high morbidity, mortality, and
disability rate. Persistent ischemia of brain tissue can cause irreversible damage to neurons …

Licochalcone a improves cardiac functions after ischemia-reperfusion via reduction of ferroptosis in rats

JH Lin, KT Yang, PC Ting, WS Lee, DJ Lin… - European Journal of …, 2023 - Elsevier
Myocardial ischemia-reperfusion (I/R) injury triggers several cell death types, including
apoptosis, autophagy, and ferroptosis. Licochalcone A (LCA), a natural flavonoid compound …

Mitochondria‐associated endoplasmic reticulum membranes tethering protein VAPB‐PTPIP51 protects against ischemic stroke through inhibiting the activation of …

M Li, Y Zhang, G Yu, L Gu, H Zhu… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims Mitochondria‐associated endoplasmic reticulum membranes (MAMs) serve as a
crucial bridge connecting the endoplasmic reticulum (ER) and mitochondria within cells …

[HTML][HTML] Microglia Autophagy Mediated by TMEM166 Promotes Ischemic Stroke Secondary to Carotid Artery Stenosis

L Li, PR Krafft, N Zeng, R Duan, X Qi, A Shao… - Aging and …, 2024 - ncbi.nlm.nih.gov
Ischemic stroke can be a serious complication of selective carotid endarterectomy (CEA) in
patients with carotid artery stenosis (CAS). The underlying risk factors and mechanisms of …

Bibliometric analysis and visualized study of research on autophagy in ischemic stroke

J Chen, G Chen, X Xu, L Chen, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Aims: To summarize and clarify the current research status and indicate possible future
directions in the field of autophagy in ischemic stroke, we performed a comprehensive and …

Autophagy and mitophagy-related extracellular mitochondrial dysfunction of cerebrospinal fluid cells in patients with hemorrhagic moyamoya disease

DH Youn, N Kim, A Lee, SW Han, JT Kim, EP Hong… - Scientific Reports, 2023 - nature.com
We aimed to investigate whether mitochondrial dysfunction in extracellular cerebrospinal
fluid (CSF), which is associated with autophagy and mitophagy, might be involved in …

[HTML][HTML] Identification of endoplasmic reticulum stress genes in human stroke based on bioinformatics and machine learning

N Jiang, MSC Wang, B Xie, H Xie, A Wu… - Neurobiology of …, 2024 - Elsevier
After ischemic stroke (IS), secondary injury is intimately linked to endoplasmic reticulum (ER)
stress and body-brain crosstalk. Nonetheless, the underlying mechanism systemic immune …

Role of autophagy in ischemic stroke: insights from animal models and preliminary evidence in the human disease

R Stanzione, D Pietrangelo, M Cotugno… - Frontiers in Cell and …, 2024 - frontiersin.org
Stroke represents a main cause of death and permanent disability worldwide. The molecular
mechanisms underlying cerebral injury in response to the ischemic insults are not …