[HTML][HTML] REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics

RL Carhart-Harris, KJ Friston - Pharmacological reviews, 2019 - ASPET
This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Machine learning in mental health: a scoping review of methods and applications

ABR Shatte, DM Hutchinson, SJ Teague - Psychological medicine, 2019 - cambridge.org
BackgroundThis paper aims to synthesise the literature on machine learning (ML) and big
data applications for mental health, highlighting current research and applications in …

Serotonin and brain function: a tale of two receptors

RL Carhart-Harris, DJ Nutt - Journal of psychopharmacology, 2017 - journals.sagepub.com
Previous attempts to identify a unified theory of brain serotonin function have largely failed to
achieve consensus. In this present synthesis, we integrate previous perspectives with new …

The entropic brain-revisited

RL Carhart-Harris - Neuropharmacology, 2018 - Elsevier
The entropic brain hypothesis proposes that within upper and lower limits, after which
consciousness may be lost, the entropy of spontaneous brain activity indexes the …

Prediction of psychosis across protocols and risk cohorts using automated language analysis

CM Corcoran, F Carrillo, D Fernández‐Slezak… - World …, 2018 - Wiley Online Library
Language and speech are the primary source of data for psychiatrists to diagnose and treat
mental disorders. In psychosis, the very structure of language can be disturbed, including …

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials

L Jerome, AA Feduccia, JB Wang, S Hamilton… - …, 2020 - Springer
Rationale Posttraumatic stress disorder (PTSD) is a chronic condition that has wide-ranging
negative effects on an individual's health and interpersonal relationships. Treatments with …

[HTML][HTML] Automated analysis of free speech predicts psychosis onset in high-risk youths

G Bedi, F Carrillo, GA Cecchi, DF Slezak, M Sigman… - npj …, 2015 - nature.com
AIMS: In this proof-of-principle study, our aim was to test automated speech analyses
combined with Machine Learning to predict later psychosis onset in youths at clinical high …

3, 4-Methylenedioxymethamphetamine-assisted psychotherapy for treatment of chronic posttraumatic stress disorder: a randomized phase 2 controlled trial

M Ot'alora G, J Grigsby, B Poulter… - Journal of …, 2018 - journals.sagepub.com
Background: Posttraumatic stress disorder often does not resolve after conventional
psychotherapies or pharmacotherapies. Pilot studies have reported that 3, 4 …

Using language processing and speech analysis for the identification of psychosis and other disorders

CM Corcoran, GA Cecchi - Biological Psychiatry: Cognitive Neuroscience …, 2020 - Elsevier
Increasingly, data-driven methods have been implemented to understand psychopathology.
Language is the main source of information in psychiatry and represents “big data” at the …

[HTML][HTML] Anomalies in language as a biomarker for schizophrenia

JN De Boer, SG Brederoo, AE Voppel… - Current opinion in …, 2020 - journals.lww.com
Language disturbances are a key feature of schizophrenia. Although in its early stages, the
emerging field of research focused on computational linguistics suggests an important role …