Candida glabrata, Candida parapsilosis and Candida tropicalis: biology, epidemiology, pathogenicity and antifungal resistance

S Silva, M Negri, M Henriques, R Oliveira… - FEMS microbiology …, 2012 - academic.oup.com
The incidence of infections caused by Candida species (candidosis) has increased
considerably over the past three decades, mainly due to the rise of the AIDS epidemic, an …

An Update on Candida tropicalis Based on Basic and Clinical Approaches

DL Zuza-Alves, WP Silva-Rocha… - Frontiers in …, 2017 - frontiersin.org
Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …

Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Antifungal resistance and new strategies to control fungal infections

P Vandeputte, S Ferrari… - International journal of …, 2012 - Wiley Online Library
Despite improvement of antifungal therapies over the last 30 years, the phenomenon of
antifungal resistance is still of major concern in clinical practice. In the last 10 years the …

Mechanisms of Candida Biofilm Drug Resistance

HT Taff, KF Mitchell, JA Edward, DR Andes - Future microbiology, 2013 - Taylor & Francis
Candida commonly adheres to implanted medical devices, growing as a resilient biofilm
capable of withstanding extraordinarily high antifungal concentrations. As currently available …

Genome-wide analysis of experimentally evolved Candida auris reveals multiple novel mechanisms of multidrug resistance

H Carolus, S Pierson, JF Muñoz, A Subotić, RB Cruz… - MBio, 2021 - Am Soc Microbiol
Candida auris is globally recognized as an opportunistic fungal pathogen of high concern,
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance

KR Healey, Y Zhao, WB Perez, SR Lockhart… - Nature …, 2016 - nature.com
The fungal pathogen Candida glabrata has emerged as a major health threat since it readily
acquires resistance to multiple drug classes, including triazoles and/or echinocandins. Thus …

Candida glabrata: a review of its features and resistance

CF Rodrigues, S Silva, M Henriques - European journal of clinical …, 2014 - Springer
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and
vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous …

Emerging multidrug-resistant Candida species

AL Colombo, JN de Almeida Júnior… - Current Opinion in …, 2017 - journals.lww.com
We checked all papers published along the last 10 years describing epidemiological,
diagnostic, and clinical aspects of infections by MDR Candida spp., with emphasis on C …