Connecting metabolome and phenotype: recent advances in functional metabolomics tools for the identification of bioactive natural products

GA Vitale, C Geibel, V Minda, M Wang, AT Aron… - Natural Product …, 2024 - pubs.rsc.org
Covering: 1995 to 2023Advances in bioanalytical methods, particularly mass spectrometry,
have provided valuable molecular insights into the mechanisms of life. Non-targeted …

Regulating the electrochemical reduction kinetics by the steric hindrance effect for a robust Zn metal anode

S Yang, A Chen, Z Tang, Z Wu, P Li, Y Wang… - Energy & …, 2024 - pubs.rsc.org
The parasitic side reactions and dendrite growth of the Zn metal anode are two primary
issues restricting the practical application of Zn-ion batteries (ZIBs). The contradiction …

Perspectives on nuclear magnetic resonance spectroscopy in drug discovery research

J Caceres-Cortes, B Falk, L Mueller… - Journal of Medicinal …, 2024 - ACS Publications
The drug discovery landscape has undergone a significant transformation over the past
decade, owing to research endeavors in a wide range of areas leading to strategies for …

[HTML][HTML] Structural materials meet synthetic biology in biomedical applications

X Zhang, M Fussenegger - Materials Today, 2023 - Elsevier
This review summarizes recent progress at the confluence of structural biomaterials
research and synthetic biology, focusing on biomedical applications involving programmed …

Conformational Analysis of 1, 5-Diaryl-3-Oxo-1, 4-Pentadiene Derivatives: A Nuclear Overhauser Effect Spectroscopy Investigation

K Belov, V Brel, V Sobornova, I Fedorova… - International Journal of …, 2023 - mdpi.com
1, 5-Diaryl-3-Oxo-1, 4-Pentadiene derivatives are intriguing organic compounds with a
unique structure featuring a pentadiene core, aryl groups, and a ketone group. This study …

Tandocyclinones A and B, Ether Bridged C-Glycosyl Benz[a]anthracenes from an Intertidal Zone Streptomyces sp.

TH Huynh, ES Bae, BE Heo, J Lee, JS An, Y Kwon… - Marine Drugs, 2023 - mdpi.com
Two new proton-deficient metabolites, tandocyclinones A and B (1 and 2), were discovered
via the chemical profiling of the Streptomyces sp. strain TDH03, which was isolated from a …

Advanced Structure Analysis Reveals a Transient Portimine B Hydrate

JS Wood, J Tang, WK Strangman… - Journal of Natural …, 2024 - ACS Publications
Portimine B was isolated from an extract derived from the dinoflagellate Vulcanodinium
rugosum, a known producer of the closely related portimine A. Initial molecular …

[HTML][HTML] Computational NMR Study of Benzothienoquinoline Heterohelicenes

VA Semenov, GE Martin, LB Krivdin - International Journal of Molecular …, 2024 - mdpi.com
Early NMR studies of several heterohelicenes containing an annular nitrogen atom and a
thiophene ring in their structure suggested the possibility of the lengthening of the carbon …

Overcoming NMR line broadening of nitrogen containing compounds: A simple solution

J Ma, Q Ye, RA Green, J Gurak, S Ayers… - Magnetic …, 2024 - Wiley Online Library
This study presents a straightforward solution to the challenge of elucidating the structures of
nitrogen containing compounds undergoing isomerization. When spectral line broadening …

Development of a system for computer-assisted structure elucidation of small organic compounds

M Wenk - 2023 - db-thueringen.de
An unambiguous interpretation and evaluation of nuclear magnetic resonance (NMR) data
for the elucidation of chemical structures can become a challenge for organic or natural …