Viral proteins recognized by different TLRs

R Zhou, L Liu, Y Wang - Journal of Medical Virology, 2021 - Wiley Online Library
Virus invasion activates the host's innate immune response, inducing the production of
numerous cytokines and interferons to eliminate pathogens. Except for viral DNA/RNA, viral …

The role of glycosyltransferases in colorectal cancer

C Fernández-Ponce, N Geribaldi-Doldán… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the main causes of cancer death in the world. Post-
translational modifications (PTMs) have been extensively studied in malignancies due to its …

In chronic hepatitis C infection, myeloid-derived suppressor cell accumulation and T cell dysfunctions revert partially and late after successful direct-acting antiviral …

V Telatin, F Nicoli, C Frasson, N Menegotto… - Frontiers in cellular …, 2019 - frontiersin.org
Chronic HCV infection is characterized by several immunological alterations, such as the
accumulation of suppressor cells and of hyperactivated T lymphocytes. However, it is …

DNA methyltransferases in virus‐associated cancers

J Charostad, A Astani, H Goudarzi… - Reviews in medical …, 2019 - Wiley Online Library
Human tumor viruses are either casually linked or contribute in the development of human
cancers. Viruses can stimulate oncogenesis through affecting diverse biological pathways in …

Modulation of the immune system in chronic hepatitis C and during antiviral interferon-free therapy

A Urbanowicz, R Zagożdżon, M Ciszek - Archivum immunologiae et …, 2019 - Springer
The treatment of patients with chronic hepatitis C virus (HCV) infection has changed
tremendously over the past 2 years, with an increasing variety of all-oral direct-acting …

Ascaris lumbricoides coinfection reduces tissue damage by decreasing IL-6 levels without altering clinical evolution of pulmonary tuberculosis or Th1/Th2/Th17 …

JHA Santos, S Bührer-Sékula, GC Melo… - Revista da Sociedade …, 2019 - SciELO Brasil
INTRODUCTION: Immunological control of Mycobacterium tuberculosis infection is
dependent on the cellular immune response, mediated predominantly by Th1 type CD4+ T …

Assessment of the housing improvement program for Chagas disease control in the Northwestern municipalities of Rio Grande do Sul, Brazil

CV Santos, C Bedin, TS Wilhelms… - Revista da Sociedade …, 2016 - SciELO Brasil
Abstract INTRODUCTION: The Housing Improvement Program for Chagas Disease Control
(HIPCDC) was established in 2001 in Northwestern Rio Grande do Sul State, aiming to …

Immune response of Th17-associated cytokines by peripheral blood mononuclear cells from patients with chronic hepatitis C virus infection

MS Cabral, TPS Santos, PL Santos, MI Schinoni… - Cytokine, 2018 - Elsevier
Hepatitis C virus (HCV) chronic infection causes severe cellular immune dysfunction. Here,
we investigated the production of Th17-associated cytokines by peripheral blood …

Potential roles of core and core+ 1 proteins during the chronic phase of hepatitis C virus infection

A Malekshahi, A Alamdary, A Safarzadeh… - Future …, 2023 - Taylor & Francis
The HCV Core protein is a multifunctional protein that interacts with many viral and cellular
proteins. In addition to the encapsidation of the viral genome, it can disturb various cellular …

HCV Core Protein–ISX Axis Promotes Chronic Liver Disease Progression via Metabolic Remodeling and Immune Suppression

LT Wang, SN Wang, SS Chiou, JP Tsai… - Advanced …, 2023 - Wiley Online Library
Chronic hepatitis C virus (HCV) infection is an important public health issue. However,
knowledge on how the virus remodels the metabolic and immune response toward hepatic …