Since the discovery of the chromosome 9 open reading frame 72 (C9orf72) repeat
expansion mutation in 2011 as the most common genetic abnormality in amyotrophic lateral …

Background Frontotemporal lobar degeneration (FTLD) and primary psychiatric disorders
(PPD) are characterised by overlapping clinical features but different aetiologies. Here, we …

Background Neuroinflammation plays a significant role in the progression of frontotemporal
dementia (FTD). However, the association between peripheral inflammatory factors and …

Frontotemporal dementia and amyotrophic lateral sclerosis are neurodegenerative diseases
with considerable clinical, genetic and pathological overlap. The most common cause of …

Background Inflammation has been proposed as a crucial player in neurodegeneration,
including Frontotemporal Dementia (FTD). A few studies on sporadic FTD lead to …

Background Measuring systemic inflammatory markers may improve clinical prognosis and
help identify targetable pathways for treatment in patients with autosomal dominant forms of …

Extrapyramidal (EP) symptoms are a known feature in a subpopulation of patients with
behavioral variant frontotemporal dementia (bvFTD). Concomitant EP symptoms with FTD …

Introduction Frontotemporal dementia (FTD) is a neurodegenerative disorder for which there
is no effective pharmacological treatment. Recently, interneuron activity responsible for fast …

Background: Exposure to repetitive head impacts (RHI) is associated with increased risk for
chronic traumatic encephalopathy (CTE), a neurodegenerative tauopathy, and other …

Frontotemporal dementia (FTD) encompasses a spectrum of disorders characterized by
distinct behavioral, cognitive, and motor symptoms. Deficits in interoception and allostasis …