The development of chronic pain is considered a major complication after surgery. Basic
science research in animal models helps us understand the transition from acute to chronic …

Effective prevention of chronic postoperative pain is an important clinical goal, informed by a
growing body of studies. Peri‐operative regional anaesthesia remains one of the most …

Background Atrial fibrillation and delirium are common consequences of cardiac surgery.
Dexmedetomidine has unique properties as sedative agent and might reduce the risk of …

In the present meta-analysis, we assessed the efficacy and safety of intravenous
administration of dexmedetomidine (DEX) compared with placebo or opioids for acute …

Abstract Editor's Perspective What We Already Know about This Topic The intraoperative
administration of methadone is effective in reducing postoperative pain Preventative …

Objectives: The aim was to compare the long-term outcomes of low-dose dexmedetomidine
versus placebo in a randomized controlled trial (ChiCTR-TRC-10000802). Background: Low …

Background Post-mastectomy pain syndrome (PMPS) is a surgical complication of breast
surgery characterized by chronic neuropathic pain. The development of PMPS is …

Özet Ağrı tedavisi hastalar için temel bir haktır. Ağrı kontrolündeki farmakolojik tedavi
modaliteleri ve müdahalelerindeki gelişmelere rağmen, postoperatif ağrı yönetimindeki …

Painful scars can develop after surgery or trauma, with symptoms ranging from a minor itch
to intractable allodynia. The problem of the painful scar may involve both intraneural and …

Background Postoperative nausea and vomiting (PONV) is the major complication related to
general anesthesia, occurring in 60–80% of patients after thyroidectomy. The objective of …