Control of the post-infarct immune microenvironment through biotherapeutic and biomaterial-based approaches

SS Soni, AM D'Elia, CB Rodell - Drug delivery and translational research, 2023 - Springer
Ischemic heart failure (IHF) is a leading cause of morbidity and mortality worldwide, for
which heart transplantation remains the only definitive treatment. IHF manifests from …

TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis

FY Liu, D Fan, Z Yang, N Tang, Z Guo, SQ Ma… - Cell death & …, 2019 - nature.com
The poor prognosis of patients with acute myocardial infarction is partially attributed to a
large number of cardiomyocyte apoptosis, necrosis, limited cardiac healing and …

TLR9-HIF-1α-VEGF axis is essential for HMGB1-mediate post-myocardial infarction tissue repair

FY Liu, D Fan, Z Yang, N Tang, Z Guo… - Available at SSRN …, 2019 - papers.ssrn.com
Background: Toll-like receptor 9 (TLR9) as an essential part of the innate immune system
plays a vital role in regulating cardiomyocyte survival and wound healing. During hypoxia …