Supervised learning plays a key role in the operation of many biological and artificial neural
networks. Analysis of the computations underlying supervised learning is facilitated by the …

The mushroom bodies are distinctive neuropils in the protocerebral brain segments of many
protostomes. A defining feature of mushroom bodies is their intrinsic neurons, masses of …

Cerebellar granule cells, which constitute half the brain's neurons, supply Purkinje cells with
contextual information necessary for motor learning, but how they encode this information is …

Cerebellar granule cells constitute the majority of neurons in the brain and are the primary
conveyors of sensory and motor-related mossy fiber information to Purkinje cells. The …

The ability of the brain to rapidly process information from multiple pathways is critical for
reliable execution of complex sensory-motor behaviors, yet the cellular mechanisms …

Sensory integration difficulties have been reported in autism, but their underlying brain-
circuit mechanisms are underexplored. Using five autism-related mouse models …

Classical feed-forward inhibition involves an excitation–inhibition sequence that enhances
the temporal precision of neuronal responses by narrowing the window for synaptic …

The cerebellum integrates sensory stimuli and motor actions to enable smooth coordination
and motor learning. Here we harness the innate behavioral repertoire of the larval zebrafish …

The segregation of the readily releasable pool of synaptic vesicles (RRP) in sub-pools that
are differentially poised for exocytosis shapes short-term plasticity. However, the frequency …

Recurrent deletions at the 22q11. 2 locus have been established as a strong genetic risk
factor for the development of schizophrenia and cognitive dysfunction. Individuals with …