While the liver demonstrates remarkable resilience during aging, there is growing evidence
that it undergoes all the cellular hallmarks of aging, which increases the risk of liver and …

Ageing is a complex biological process in which a gradual decline in physiological fitness
increases susceptibility to diseases such as neurodegenerative disorders and cancer …

Given the dramatic increase in ageing populations, it is of great importance to understand
the genetic and molecular determinants of healthy ageing and longevity. Semi …

Telomere length (TL) has become a biomarker of increasing interest within ecology and
evolutionary biology, and has been found to predict subsequent survival in some recent …

Males and females often age at different rates resulting in longevity 'gender gaps', where
one sex outlives the other. Why the sexes have different lifespans is an age‐old question …

Telomeres are nucleoprotein structures, located at the ends of chromosomes and are
subject to shortening at each cycle of cell division. They prevent chromosomal ends from …

The geriatric populations of many countries are growing rapidly and they present major
problems to healthcare infrastructures from both medical and economic perspectives. The …

Twin studies show that genetic differences account for about a quarter of the variance in
adult human lifespan. Common polymorphisms that have a modest effect on lifespan have …

Telomere length (TL) is emerging as a biomarker for aging and survival. To evaluate factors
influencing this trait, we measured TL in a large homogeneous population, estimated the …

Aging is a biological process that affects most cells, organisms and species. Telomeres have
been postulated as a universal biological clock that shortens in parallel with aging in cells …