Despite the advancements in the development of anticancer agents, more effective and
safer anticancer drugs still need to be developed as the current agents cause unwanted side …

Coumarin derivatives are important class of natural plant metabolites that offer variety of
biological activities. They can also be derived synthetically, and a wide variety of synthetic …

Heading the list of the critical health-related issues worldwide, cancer continues to be a one
of the most serious life-threatening diseases. The rate of cancer-related mortality is at …

Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …

Coumarin and its derivatives are widely used as scaffolds in the synthesis of new
heterocyclic systems. This review focuses on current developments in the synthesis of …

Over the past few decades, the dynamic progress in the synthesis and screening of
heterocyclic compounds against various targets has made a significant contribution in the …

In the present study we designed and synthesized 26 coumarin clubbed chalcone hybrids (1–
13 and 14–26) in good yields (54.32–74.25%) and further tested for their antimicrobial and …

Purpose Cancer is one of the most common and fatal disease, chemotherapy is the major
treatment against many cancer types. The anti-apoptotic BCL-2 protein's expression was …

In this study, we have synthesized a new series of benzimidazole-triazole hybrids as
galectin-1 (gal-1) mediated apoptosis-inducing agents, and evaluated for their potential …

The structural motif of coumarins is related with various biological activities and
pharmacological properties. Both natural coumarin extracted from various plants or a new …