CD8+ tissue resident memory T cells (TRM cells) are essential for immune defence against
pathogens and malignancies, and the molecular processes that lead to TRM cell formation …

In 1986, Mosmann and Coffman identified 2 functionally distinct subsets of activated CD4 T
cells, Th1 and Th2 cells, being key in distinct T cell mediated responses. Over the past three …

Non-alcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease that can
progress to liver fibrosis. Recent clinical advance suggests a reversibility of liver fibrosis, but …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Immune system dysfunction is paramount in coronavirus disease 2019 (COVID-19) severity
and fatality rate. Mucosal-associated invariant T (MAIT) cells are innate-like T cells involved …

T cells differentiate into functionally distinct states upon antigen encounter. These states are
delineated by different cell surface markers for murine and human T cells, which hamper …

Tissue-resident memory CD8+ T cells (TRM cells) are crucial in protecting against
reinvading pathogens, but the impact of reinfection on their tissue confinement and …

Skin-resident CD8+ T cells include distinct interferon-γ–producing [tissue-resident memory T
type 1 (TRM1)] and interleukin-17 (IL-17)–producing (TRM17) subsets that differentially …

Tissue-resident memory CD8+ T cells (TRM) constitute a noncirculating memory T cell
subset that provides early protection against reinfection. However, how TRM arise from …

Tumor-infiltrating lymphocytes (TILs), in general, and especially CD8+ TILs, represent a
favorable prognostic factor in non–small cell lung cancer (NSCLC). The tissue origin …