Breast cancer is one of the most frequent cancer types worldwide and the first cause of
cancer-related deaths in women. Although significant therapeutic advances have been …

Cancers of the reproductive organs have a strong association with mitochondrial defects,
and a deeper understanding of the role of this organelle in preneoplastic–neoplastic …

Background The epithelial-mesenchymal transition (EMT) is crucial for metastasis and
positively regulated by calcium-related signaling. The melastatin-related transient receptor …

Metastasis leads to poor prognosis and reduced disease-free survival in breast cancer
patients, particularly in those with triple-negative breast cancer (TNBC) which is resistant to …

The negative health effects of bisphenol A (BPA) due to its estrogenic activity result in the
increasing usage of alternative bisphenols (BPs) including bisphenol AF (BPAF). To …

Calcium is a versatile element that participates in cell signaling for a wide range of cell
processes such as death, cell cycle, division, migration, invasion, metabolism, differentiation …

Objective T cell receptor-associated transmembrane adaptor 1 (TRAT1) is one of the hub
genes regulating T cell receptors (TCRs). Herein, the roles of TRAT1 in the prognosis and …

Purpose: 3, 3′-Diindolylmethane (DIM), derived from indole-3-carbinol (I3C) in the Brassica
species of cruciferous vegetables, has anticancer effects, but its exact underlying …

Voltage-gated calcium channels and estrogen receptors are essential players in uterine
physiology, and their association with different calcium signaling pathways contributes to …

Aim Sepsis is a life-threatening disease with high mortality worldwide. Septic females have
lower severity and mortality than the males, suggesting estrogen exerts a protective action …