Synthesis and Evaluation of Tricarbonyl 99mTc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich …

JY Choi, RM Iacobazzi, M Perrone, N Margiotta… - International journal of …, 2016 - mdpi.com
The 18-kDa translocator protein (TSPO) levels are associated with brain, breast, and
prostate cancer progression and have emerged as viable targets for cancer therapy and …

[PDF][PDF] New leads for fragment-based design of rhenium/technetium radiopharmaceutical agents

A Brink, JR Helliwell - IUCrJ, 2017 - journals.iucr.org
Multiple possibilities for the coordination of fac-[Re (CO) 3 (H2O) 3]+ to a protein have been
determined and include binding to Asp, Glu, Arg and His amino-acid residues as well as to …

[PDF][PDF] Formation of a highly dense tetra-rhenium cluster in a protein crystal and its implications in medical imaging

A Brink, JR Helliwell - IUCrJ, 2019 - journals.iucr.org
The fact that a protein crystal can serve as a chemical reaction vessel is intrinsically
fascinating. That it can produce an electron-dense tetranuclear rhenium cluster compound …

Water-Soluble Rhenium Phosphine Complexes Incorporating the Ph2C(X) Motif (X = O, NH): Structural and Cytotoxicity Studies

AF Alshamrani, TJ Prior, BP Burke, DP Roberts… - Inorganic …, 2020 - ACS Publications
Reaction of [ReOCl3 (PPh3) 2] or [ReO2I (PPh3) 2] with 2, 2′-diphenylglycine (dpgH2) in
refluxing ethanol afforded the air-stable complex [ReO (dpgH)(dpg)(PPh3)](1). Treatment of …

Synthesis and Evaluation of Technetium‐99m‐Labeled Bioreductive Pharmacophores Conjugated with Amino Acids and Peptides for Tumor Imaging

R Baishya, DK Nayak, S Karmakar… - Chemical Biology & …, 2015 - Wiley Online Library
Development of molecular imaging agents to target tumor has become a major trend in
nuclear medicine. With the aim to develop new potential 99mTc‐radiopharmaceuticals for …

Selective complexation of α-amino acids and simple peptides via their carboxylate groups

R Schnitter, D Gallego, B Kersting - Dalton Transactions, 2014 - pubs.rsc.org
The complexation of anions of selected α-amino acids (alanine, valine, proline, tyrosine) and
small peptides (L-alanyl-L-alanine, L-alanyl-L-alanyl-L-alanine, and L-alanyl-L-alanyl-L …

New leads for fragment-based design of rhenium/technetium radiopharmaceutical agents

A Brinka, JR Helliwell, P Lightfoot - International Union of …, 2017 - go.gale.com
Multiple possibilities for the coordination of fac-[[Re [(CO). sub. 3][([H. sub. 2] O). sub. 3]].
sup.+] to a protein have been determined and include binding to Asp, Glu, Arg and His …