BX Du, Y Qin, YF Jiang, Y Xu, SM Yiu, H Yu, JY Shi - Drug discovery today, 2022 - Elsevier
The screening of compound–protein interactions (CPIs) is one of the most crucial steps in finding hit and lead compounds. Deep learning (DL) methods for CPI prediction can address …
H Wang, C Dai, Y Wen, X Wang, W Liu… - Briefings in …, 2023 - academic.oup.com
Drug response prediction in cancer cell lines is of great significance in personalized medicine. In this study, we propose GADRP, a cancer drug response prediction model …
B Shen, F Feng, K Li, P Lin, L Ma… - Briefings in …, 2023 - academic.oup.com
Drug response prediction is an important problem in personalized cancer therapy. Among various newly developed models, significant improvement in prediction performance has …
Apprehension of drug action mechanism is paramount for drug response prediction and precision medicine. The unprecedented development of machine learning and deep …
Accumulated preclinical data are increasingly being re-used to build and validate predictive models generated by artificial intelligence (AI)[1] algorithms. Such in silico models have a …
M Zhang, H Gao, X Liao, B Ning, H Gu… - Briefings in …, 2023 - academic.oup.com
The prediction of drug–drug interactions (DDIs) is essential for the development and repositioning of new drugs. Meanwhile, they play a vital role in the fields of …
The field of omics, driven by advances in high-throughput sequencing, faces a data explosion. This abundance of data offers unprecedented opportunities for predictive …
Cancer treatment has become one of the biggest challenges in the world today. Different treatments are used against cancer; drug-based treatments have shown better results. On …
Cancer epigenetics has become increasingly popular due to the reversible nature of epigenetic changes that tend to take place during carcinogenesis. Cervical tumorigenesis in …