Recent developments in the synthesis of N‐heterocyclic compounds as α‐amylase inhibitors via in‐vitro and in‐silico analysis: Future drugs for treating diabetes

P Garg, RS Rawat, H Bhatt, S Kumar… - …, 2022 - Wiley Online Library
In nature, N‐heterocyclic compounds and their derivatives are abundant. They serve as the
building blocks of many biological entities, such as enzymes, alkaloids, hormones …

Recent advances in the synthetic chemistry of 1, 5‐benzothiazepines: A minireview

V Devi, G Singh, V Monga - Journal of Heterocyclic Chemistry, 2020 - Wiley Online Library
Benzothiazepine, a prominent “drug prejudice core”, is a heterocyclic moiety of immense
importance due to its presence in a wide range of bioactive compounds. They act as a …

Odorless isocyanide chemistry: one-pot synthesis of heterocycles via the Passerini and postmodification tandem reaction based on the in situ capture of isocyanides

N Liu, F Chao, MG Liu, NY Huang, K Zou… - The Journal of organic …, 2019 - ACS Publications
This paper reports the tandem reaction strategy of the Passerini/Staudinger/aza-Wittig
reaction based on the in situ capture of isocyanides. According to this strategy, isocyanides …

[HTML][HTML] Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents

AB Shaik, RR Bhandare, S Nissankararao… - Arabian Journal of …, 2021 - Elsevier
A series of twenty new chloropyrazine conjugated benzothiazepines (22–41) have been
synthesized with 58%–95% yields. The compounds were characterized by using different …

Synthesis, Type II diabetes inhibitory activity, antimicrobial evaluation and docking studies of indeno[1,2-c]pyrazol-4(1H)-ones

S Mor, S Sindhu - Medicinal Chemistry Research, 2020 - Springer
We report a convenient and efficient synthesis of indeno [1, 2-c] pyrazol-4 (1 H)-ones (4a‒o)
by the reaction of a variety of 2-acyl-(1 H)-indene-1, 3 (2 H)-diones (1) and 2 …

1, 5-Benzothiazepines: Recent developments in the synthetic strategies

AK Suman, A Dushad, B Singh - Tetrahedron, 2023 - Elsevier
Several heterocyclic molecular frameworks have been regarded as privileged structure in
the field of medicinal chemistry. These privileged structure or scaffolds or moieties display …

Synthesis and study of catalytic perspectives of DABCO based ionic liquid for the synthesis of 2, 3-dihydro-1, 5-benzothiazepines and 2-phenylbenzothiazoles

P Pinate, S Makone - Catalysis Letters, 2023 - Springer
In this study, a novel DABCO based dicationic acidic ionic liquid [C4H10-DABCO][HSO4] 2
has been synthesized, characterized, and applied successfully as an eco-friendly and …

[HTML][HTML] Antimicrobial evaluation and QSAR studies of 3, 6-disubstituted-11H-benzo [5, 6][1, 4] thiazino [3, 4-a] isoindol-11-ones

S Mor, S Sindhu, M Khatri, R Punia, H Sandhu… - European Journal of …, 2022 - Elsevier
The antimicrobial evaluation of a series of twenty 3, 6-disubstituted-11H-benzo [5, 6][1, 4]
thiazino [3, 4-a] isoindol-11-ones 8a–t was done against two Gram-positive bacterial strains …

[PDF][PDF] Synthesis, Type II diabetes inhibitory activity, antimicrobial evaluation, and docking studies of N'-arylidene-2-((7-methylbenzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazol …

S Mor, S Sindhu, M Khatri, R Punia… - European Journal of …, 2022 - academia.edu
Diabetes mellitus is a metabolic disorder resulting from insufficient insulin secretion
characterized by chronic hyperglycemia due to high-calorie diets rich in carbohydrates, fats …