Postoperative chemotherapy improves survival in patients with resected high‐risk Stage II colorectal cancer: results of a systematic review and meta‐analysis
C Simillis, H Singh, T Afxentiou, S Mills… - Colorectal …, 2020 - Wiley Online Library
Aim The aim was to assess the benefit of adjuvant chemotherapy in high‐risk Stage II
colorectal cancer. Method A systematic literature review and meta‐analysis was performed …
colorectal cancer. Method A systematic literature review and meta‐analysis was performed …
Adjuvant chemotherapy in elderly colorectal cancer patients
B Glimelius, E Osterman - Cancers, 2020 - mdpi.com
The value of adjuvant chemotherapy in elderly patients has been the subject of many
overviews, with opinions varying from “not effective”, since randomized trials have not been …
overviews, with opinions varying from “not effective”, since randomized trials have not been …
Differences in prognosis and underuse of adjuvant chemotherapy between elderly and non‐elderly patients in stage III colorectal cancer
T Shiraishi, H Ogawa, I Shioi, N Ozawa… - Annals of …, 2023 - Wiley Online Library
Aim We aimed to clarify the use of adjuvant chemotherapy and the prognosis of elderly
colorectal cancer patients compared with non‐elderly patients, and the usefulness of …
colorectal cancer patients compared with non‐elderly patients, and the usefulness of …
Oxaliplatin-Based Adjuvant Chemotherapy in Older Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 12 Trials
PURPOSE A number of studies suggest that older patients may have reduced or no benefit
from the addition of oxaliplatin to fluoropyrimidines as adjuvant chemotherapy for stage III …
from the addition of oxaliplatin to fluoropyrimidines as adjuvant chemotherapy for stage III …
Impact of age on toxicity and efficacy of 5-FU-based combination chemotherapy among patients with metastatic colorectal cancer; a pooled analysis of five …
O Abdel-Rahman, H Karachiwala - International Journal of Colorectal …, 2019 - Springer
Objective To assess the impact of age on toxicity and efficacy outcomes of metastatic
colorectal cancer treated with 5FU-based combination chemotherapy. Methods Project Data …
colorectal cancer treated with 5FU-based combination chemotherapy. Methods Project Data …
Immunoscore clinical utility to identify good prognostic colon cancer stage II patients with high-risk clinico-pathological features for whom adjuvant treatment may be …
J Galon, F Hermitte, B Mlecnik, F Marliot, CB Bifulco… - 2019 - ascopubs.org
487 Background: Immunoscore Colon is an IVD test predicting the risk of relapse in early-
stage colon cancer (CC) patients, by measuring the host immune response at the tumor site …
stage colon cancer (CC) patients, by measuring the host immune response at the tumor site …
Comorbidities, timing of treatments, and chemotherapy use influence outcomes in stage III colon cancer: a population-based European study
P Minicozzi, M Vicentini, K Innos, C Castro… - European Journal of …, 2020 - Elsevier
Introduction For stage III colon cancer (CC), surgery followed by chemotherapy is the main
curative approach, although optimum times between diagnosis and surgery, and surgery …
curative approach, although optimum times between diagnosis and surgery, and surgery …
Age-related differences in progression patterns, follow-up strategies, and postoperative outcomes in locally advanced rectal cancer: insights from a large-scale …
Y Yu, H Wu, J Qiu, L Hong, S Wu… - Therapeutic …, 2024 - journals.sagepub.com
Background: Locally advanced rectal cancer (LARC) presents significant treatment
challenges, particularly as patient age may influence disease progression and treatment …
challenges, particularly as patient age may influence disease progression and treatment …
Treatment of Glioblastoma in the Elderly
RA Harrison, JF de Groot - Drugs & Aging, 2018 - Springer
Clinical research in neuro-oncology frequently classifies patients over 60–70 years of age
as 'elderly', a designation intended to identify patients with the disease characteristics …
as 'elderly', a designation intended to identify patients with the disease characteristics …
Adjuvant chemotherapy does not provide survival benefits to elderly patients with stage II colon cancer
To date, the effect of adjuvant chemotherapy after curative resection in patients with stage II
colon cancer remains controversial. Still, little is known about the effects of adjuvant …
colon cancer remains controversial. Still, little is known about the effects of adjuvant …