Sarcopenia is now clinically defined as a loss of muscle mass coupled with functional
deterioration (either walking speed or distance or grip strength). Based on the FRAX studies …

Pain is a complex experience with far-reaching organismal influences ranging from
biological factors to those that are psychological and social. Such influences can serve as …

DEK and miR-5100 play critical roles in many steps of cancer initiation and progression and
are directly or indirectly regulated by most promoters and repressors. LEF1-AS1 as a long …

Objectives Drug abuse is one of the most severe global social and public health problems,
especially in China. However, objective blood biomarkers that are easy to detect are still in …

Emerging evidence demonstrates functional contributions of microRNAs (miRNAs) to μ-
opioid receptor (MOR) signaling, but the information so far has been mostly limited to their …

Substance use disorder (SUD) is a growing health problem that affects several millions of
people worldwide, resulting in negative socioeconomic impacts and increased health care …

Prenatal opioid exposure (POE) is commonly associated with neonatal opioid withdrawal
syndrome (NOWS), which is characterized by a broad variability in symptoms and severity …

We examined the role of toll-like receptors (TLRs) and proinflammatory cytokine signaling
pathways in the prefrontal cortex (PFC) in anxiety-like behaviors after repeated use of …

Chronic exposure to drugs of abuse produces profound changes in gene expression and
neural activity associated with drug-seeking and taking behavior. Dysregulation of opioid …

Multiple sclerosis (MS) is a neurodegenerative and demyelinating autoimmune disease
mediated by autoreactive T cells that affects the central nervous system (CNS) …