[HTML][HTML] Analytical methods for amatoxins: A comprehensive review

I Barbosa, C Domingues, F Ramos… - Journal of Pharmaceutical …, 2023 - Elsevier
Amatoxins are toxic bicyclic octapeptides found in certain wild mushroom species,
particularly Amanita phalloides. These mushrooms contain predominantly α-and β-amanitin …

Human poisoning from poisonous higher fungi: Focus on analytical toxicology and case reports in forensic toxicology

E Flament, J Guitton, JM Gaulier, Y Gaillard - Pharmaceuticals, 2020 - mdpi.com
Several families of higher fungi contain mycotoxins that cause serious or even fatal
poisoning when consumed by humans. The aim of this review is to inventory, from an …

Molecular recognition mechanism of an anti-amatoxins mAb and its application in centrifugal disk-based immunoassay

J Zhu, J Kou, L Ma, X Yu, C Li, Z Wang… - Journal of Agricultural …, 2023 - ACS Publications
Amatoxins are polypeptides that cause 90% of fatalities from accidental ingestion of
poisonous mushrooms. Unfortunately, there are no specific antidotes against amatoxins …

Profiling of Amatoxins and Phallotoxins in the Genus Lepiota by Liquid Chromatography Combined with UV Absorbance and Mass Spectrometry

RM Sgambelluri, S Epis, D Sassera, H Luo… - Toxins, 2014 - mdpi.com
Species in the mushroom genus Lepiota can cause fatal mushroom poisonings due to their
content of amatoxins such as α-amanitin. Previous studies of the toxin composition of …

A simple and high-throughput analysis of amatoxins and phallotoxins in human plasma, serum and urine using UPLC-MS/MS combined with PRiME HLB μElution …

S Zhang, Y Zhao, H Li, S Zhou, D Chen, Y Zhang… - Toxins, 2016 - mdpi.com
Amatoxins and phallotoxins are toxic cyclopeptides found in the genus Amanita and are
among the predominant causes of fatal food poisoning in China. In the treatment of Amanita …

[HTML][HTML] TurboFlow 在线净化-液相色谱-串联质谱法快速检测人尿中鹅膏肽类毒素

F Li, QIU Fengmei, YU Xinwei - Chinese Journal of …, 2021 - ncbi.nlm.nih.gov
鹅膏肽类毒素是一类环状多肽类蘑菇毒素, 中毒后会造成急性肝损伤, 病死率非常高。
我国因误食野生毒蘑菇导致的中毒事件常有发生, 测定人尿中鹅膏肽类毒素的浓度 …

Detection of α-, β-, and γ-amanitin in urine by LC-MS/MS using 15N10-α-amanitin as the internal standard

NL Abbott, KL Hill, A Garrett, MD Carter, EI Hamelin… - Toxicon, 2018 - Elsevier
The majority of fatalities from poisonous mushroom ingestion are caused by amatoxins. To
prevent liver failure or death, it is critical to accurately and rapidly diagnose amatoxin …

Rapid, sensitive, and accurate point-of-care detection of lethal amatoxins in urine

CS Bever, KD Swanson, EI Hamelin, M Filigenzi… - Toxins, 2020 - mdpi.com
Globally, mushroom poisonings cause about 100 human deaths each year, with thousands
of people requiring medical assistance. Dogs are also susceptible to mushroom poisonings …

Amanitins in wild mushrooms: the development of HPLC-UV-EC and HPLC-DAD-MS methods for food safety purposes

I Barbosa, C Domingues, RM Barbosa, F Ramos - Foods, 2022 - mdpi.com
Mushroom poisoning remains a serious food safety and health concern in some parts of the
world due to its morbidity and mortality. Identification of mushroom toxins at an early stage of …

[PDF][PDF] 在线固相萃取⁃ 液相色谱⁃ 串联质谱法检测蘑菇中毒患者尿液中痕量α⁃ 鹅膏毒肽

徐小民, 张京顺, 蔡增轩, 孟真, 黄百芬… - Chinese Journal of …, 2020 - researchgate.net
建立了在线固相萃取⁃ 液相色谱⁃ 串联质谱(online SPE⁃ LC⁃ MS/MS) 测定蘑菇中毒患者尿液
中痕量α⁃ 鹅膏毒肽的分析方法. 样品经甲酸酸化的乙腈⁃ 甲醇(5∶ 1, v/v) 沉淀蛋白质 …