Both obesity and aging are associated with the development of metabolic diseases such as
type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose …

Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development …

Macrophages comprise a majority of the resident immune cells in adipose tissue (AT) and
regulate both tissue homeostasis in the lean state and metabolic dysregulation in obesity …

Adipose tissue inflammation, as defined by macrophage accumulation, is proposed to cause
insulin resistance and systemic inflammation. Because the strength of this relationship for …

The prevalence of obesity skyrocketed over the past decades to become a significant public
health problem. Obesity is recognized as a low-grade inflammatory disease and is linked …

Obesity is epidemic and of great concern because of its comorbid and costly inflammatory-
driven complications. Extensive investigations in mice have elucidated highly coordinated …

The cardiometabolic syndrome involves a clustering of metabolic and cardiovascular factors
which increase the risk of patients developing both Type 2 Diabetes Mellitus and cardio …

Metabolic syndrome (MetS) is a cluster of metabolic disorders primarily caused by central
obesity, which results in chronic inflammation leading to hypertension, diabetes and …

(1) Introduction: Apples are a source of bioactive substances, eg, anthocyanidins and
flavonols, and dietary fiber. Their highest concentrations are observed in the skin. Metabolic …

Significance: Metabolic syndrome (MetS) prevalence continues to grow and represents a
serious public health issue worldwide. This multifactorial condition carries the risk of …