The return of the nucleus: transcriptional and epigenetic control of autophagy

J Füllgrabe, DJ Klionsky, B Joseph - Nature reviews Molecular cell …, 2014 - nature.com
Autophagy is a conserved process by which cytoplasmic components are degraded by the
lysosome. It is commonly seen as a cytoplasmic event and, until now, nuclear events were …

[HTML][HTML] MicroRNAs in apoptosis, autophagy and necroptosis

Z Su, Z Yang, Y Xu, Y Chen, Q Yu - Oncotarget, 2015 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are endogenous 22 nt non-coding RNAs that target mRNAs for
cleavage or translational repression. Numerous miRNAs regulate programmed cell death …

MiRNA-210 induces microglial activation and regulates microglia-mediated neuroinflammation in neonatal hypoxic-ischemic encephalopathy

B Li, C Dasgupta, L Huang, X Meng… - Cellular & Molecular …, 2020 - nature.com
Neuroinflammation is a major contributor to secondary neuronal injury that accounts for a
significant proportion of final brain cell loss in neonatal hypoxic-ischemic encephalopathy …

Inhibition of microRNA-210 suppresses pro-inflammatory response and reduces acute brain injury of ischemic stroke in mice

L Huang, Q Ma, Y Li, B Li, L Zhang - Experimental neurology, 2018 - Elsevier
Stroke is a leading cause of mortality and chronic neurologic disability. Yet, the successful
treatment remains limited. In this study, we investigated the efficacy and the mechanism of a …

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

MJ Millan - Progress in neurobiology, 2017 - Elsevier
The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

Increases in miR-124-3p in microglial exosomes confer neuroprotective effects by targeting FIP200-mediated neuronal autophagy following traumatic brain injury

D Li, S Huang, Z Yin, J Zhu, X Ge, Z Han, J Tan… - Neurochemical …, 2019 - Springer
In our recent study, we observed consistent increases in miR-124-3p levels in exosomes
derived from cultured BV2 microglia which was treated with repetitive traumatic brain injury …

Multiple functions of hypoxia-regulated miR-210 in cancer

Q Qin, W Furong, L Baosheng - Journal of Experimental & Clinical Cancer …, 2014 - Springer
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-
transcriptionally. miRNAs can be induced by a variety of stresses such as hypoxia, and are …

Neural stem cell therapy for stroke: A multimechanistic approach to restoring neurological function

EW Baker, HA Kinder, FD West - Brain and behavior, 2019 - Wiley Online Library
Abstract Introduction Neural stem cells (NSCs) have demonstrated multimodal therapeutic
function for stroke, which is the leading cause of long‐term disability and the second leading …

Combination of EPC-EXs and NPC-EXs with miR-126 and miR-210 overexpression produces better therapeutic effects on ischemic stroke by protecting neurons …

X Xu, H Zhang, J Li, Y Chen, W Zhong, Y Chen… - Experimental …, 2023 - Elsevier
Backgrounds/aims Neural progenitor cells (NPCs) and endothelial progenitor cell (EPCs)
exhibit synergistical effects on protecting endothelial cell functions. MiR-126 and miR-210 …

MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1

Y Li, L Mao, Y Gao, S Baral, Y Zhou, B Hu - Scientific reports, 2015 - nature.com
Previous studies have suggested that microRNA-107 (miR-107) regulates cell migration in
tumor and promotes Hypoxia Inducible Factor 1α (HIF1α) regulated angiogenesis under …