Obesity and insulin resistance: associations with chronic inflammation, genetic and epigenetic factors

A Gasmi, S Noor, A Menzel, L Pivina… - Current medicinal …, 2021 - ingentaconnect.com
Background: Obesity is known to be a multifactorial disease. In its pathogenesis, different
factors such as chronic inflammation, oxidative stress, insulin resistance, genetic factors …

Homocysteine is associated with higher risks of ischemic stroke: A systematic review and meta-analysis

NN Rabelo, JPM Telles, LZ Pipek… - PloS one, 2022 - journals.plos.org
Background High levels of homocysteine (Hct) have been associated with great risks of
ischemic stroke. However, some controversy still exists. We performed a systematic review …

[HTML][HTML] Evaluation of homocysteine level as a risk factor among patients with ischemic stroke and its subtypes

N Ashjazadeh, M Fathi, A Shariat - Iranian journal of medical …, 2013 - ncbi.nlm.nih.gov
Background: Epidemiological research has shown that increased total homocysteine (tHcy)
levels are associated with an increased risk of thromboembolic disease; however …

The role of homocysteine levels as a risk factor of ischemic stroke events: A systematic review and meta-analysis

RT Pinzon, VO Wijaya, V Veronica - Frontiers in Neurology, 2023 - frontiersin.org
Introduction Among numerous risk factors, homocysteine (Hcy) has been linked to cerebral
infarction; however, results have been inconsistent. This review aimed to conduct a meta …

Potential serum biomarkers in the pathophysiological processes of stroke

Y Miao, JK Liao - Expert review of neurotherapeutics, 2014 - Taylor & Francis
Stroke is a leading cause of death and serious long-term disability. Ischemic stroke is the
major subtype of stroke. Currently, its diagnosis is mainly dependent upon clinical symptoms …

Combination of high-sensitivity C-reactive protein and homocysteine predicts the short-term outcomes of Chinese patients with acute ischemic stroke

WJ Tu, SJ Zhao, TG Liu, DG Yang, H Chen - Neurological research, 2013 - Taylor & Francis
Background: Ischemic stroke is one of the most common causes of death worldwide. Early
and accurate prediction of outcome in acute ischemic stroke (AIS) is important and …

Plausible relationship between homocysteine and obesity risk via MTHFR gene: a meta-analysis of 38,317 individuals implementing Mendelian randomization

L Fu, Y Li, D Luo, S Deng, YQ Hu - Diabetes, Metabolic Syndrome …, 2019 - Taylor & Francis
Objective Numerous studies have explored the role of methylenetetrahydrofolate reductase
gene (MTHFR) C677T polymorphism and homocysteine (Hcy) concentration in obesity, but …

Hyperhomocysteinemia and ischemic stroke: a potential dose-response association—a systematic review and meta-analysis

M Holmen, AM Hvas, JFH Arendt - Th Open, 2021 - thieme-connect.com
Background and Purpose Previous studies suggest an association between increased
homocysteine (Hcy) and risk of ischemic stroke. Yet, it remains unknown whether a dose …

Plasma homocysteine and prognosis of acute ischemic stroke: a gender-specific analysis from CATIS randomized clinical trial

C Zhong, T Xu, T Xu, Y Peng, A Wang, J Wang… - Molecular …, 2017 - Springer
Elevated total homocysteine level (tHcy) has been hypothesized to be associated with
morbidity and mortality of stroke; however, results regarding the association between …

[PDF][PDF] 血浆同型半胱氨酸水平与脑卒中关系研究进展

张鸥, 刘洋, 蒙航娟, 丛树艳 - 中国公共卫生, 2021 - zgggws.com
同型半胱氨酸作为脑卒中的独立危险因素, 与卒中发病率, 复发率及预后均密切相关,
在不同的卒中亚型中水平各有差异, 致病机制主要涉及血管内皮损伤, 平滑肌细胞增生 …