[HTML][HTML] Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model

T Stockner, TR Montgomery, O Kudlacek… - PLoS computational …, 2013 - journals.plos.org
The high-resolution crystal structure of the leucine transporter (LeuT) is frequently used as a
template for homology models of the dopamine transporter (DAT). Although similar in …

Computational modeling of human dopamine transporter structures, mechanism and its interaction with HIV-1 transactivator of transcription

Y Yuan, X Huang, J Zhu, CG Zhan - Future medicinal chemistry, 2016 - Taylor & Francis
This is a brief review of computational modeling studies on the detailed structures and
mechanism of human dopamine transporter (hDAT), as well as its interaction with HIV-1 …

The role of local hydration and hydrogen-bonding dynamics in ion and solute release from ion-coupled secondary transporters

C Zhao, SY Noskov - Biochemistry, 2011 - ACS Publications
Recent progress in crystallographic studies of sodium-coupled secondary transporters has
revealed striking similarities in the structural organization of ion and solute binding. Previous …

HIV-Associated Neurocognitive Disorder: The Interaction Between HIV-1 and Dopamine Transporter Structure

AAE Elrashedy - Big Data Analytics in HIV/AIDS Research, 2018 - igi-global.com
In the last two decades, several advancement studies have increased the care of HIV-
infected individuals. Specifically, the development for preparation of combination …

[PDF][PDF] Future Medicinal Chemistry

Y Yuan, X Huang - researchgate.net
This is a brief review of computational modeling studies on the detailed structures and
mechanism of human dopamine transporter (hDAT), as well as its interaction with HIV-1 …